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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WEE2 All Species: 5.15
Human Site: T532 Identified Species: 9.44
UniProt: P0C1S8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C1S8 NP_001099028.1 567 62925 T532 G Y T H H G D T G V S G T H T
Chimpanzee Pan troglodytes XP_519504 455 50573 G421 D T H H G D T G V S G T H T G
Rhesus Macaque Macaca mulatta NP_001099016 568 63102 T533 G D I H H D D T G V S G T H T
Dog Lupus familis XP_532748 515 57465 A481 P S E R P S A A G L A R S R V
Cat Felis silvestris
Mouse Mus musculus Q66JT0 555 62324 E521 H I Q T P Q R E V H H C Y Y Q
Rat Rattus norvegicus Q63802 646 71478 A612 K V A A E E R A L L T D R M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520344 429 47032 S395 Q D L R Q G G S R P S A P R A
Chicken Gallus gallus NP_001026352 641 70947 R607 A K A A A E E R A L F T D R M
Frog Xenopus laevis P47817 555 61670 E521 A Q T S G K D E C S D L P P M
Zebra Danio Brachydanio rerio NP_001032299 527 59094 T493 K E A R L A A T S P Q Q S C Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54350 609 68790 A564 E Q R V N L L A V T N N P D S
Honey Bee Apis mellifera XP_624069 589 66032 I553 I A P N V A A I N N T M N A G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999796 624 68925 R573 R S F T Q L K R E L N V A K F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.7 94.3 71.9 N.A. 66.8 43 N.A. 47.7 42.1 52.9 43.5 N.A. 33.5 36.1 N.A. 39.2
Protein Similarity: 100 78.1 95.9 77.7 N.A. 76.5 56.8 N.A. 57.1 57.8 64.9 58.9 N.A. 50.7 52.6 N.A. 55.2
P-Site Identity: 100 6.6 80 6.6 N.A. 0 0 N.A. 13.3 0 13.3 6.6 N.A. 0 0 N.A. 0
P-Site Similarity: 100 6.6 80 26.6 N.A. 6.6 13.3 N.A. 20 13.3 13.3 13.3 N.A. 20 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 24 16 8 16 24 24 8 0 8 8 8 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 8 0 8 0 % C
% Asp: 8 16 0 0 0 16 24 0 0 0 8 8 8 8 0 % D
% Glu: 8 8 8 0 8 16 8 16 8 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 8 % F
% Gly: 16 0 0 0 16 16 8 8 24 0 8 16 0 0 16 % G
% His: 8 0 8 24 16 0 0 0 0 8 8 0 8 16 0 % H
% Ile: 8 8 8 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 16 8 0 0 0 8 8 0 0 0 0 0 0 8 0 % K
% Leu: 0 0 8 0 8 16 8 0 8 31 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 16 % M
% Asn: 0 0 0 8 8 0 0 0 8 8 16 8 8 0 0 % N
% Pro: 8 0 8 0 16 0 0 0 0 16 0 0 24 8 0 % P
% Gln: 8 16 8 0 16 8 0 0 0 0 8 8 0 0 16 % Q
% Arg: 8 0 8 24 0 0 16 16 8 0 0 8 8 24 0 % R
% Ser: 0 16 0 8 0 8 0 8 8 16 24 0 16 0 8 % S
% Thr: 0 8 16 16 0 0 8 24 0 8 16 16 16 8 16 % T
% Val: 0 8 0 8 8 0 0 0 24 16 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _