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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WEE2 All Species: 8.79
Human Site: T83 Identified Species: 16.11
UniProt: P0C1S8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C1S8 NP_001099028.1 567 62925 T83 S P D Q I L R T P V S H P L K
Chimpanzee Pan troglodytes XP_519504 455 50573
Rhesus Macaque Macaca mulatta NP_001099016 568 63102 T83 S P D Q I L R T P V S H P L K
Dog Lupus familis XP_532748 515 57465 T59 A K F T P P R T P S S S I H G
Cat Felis silvestris
Mouse Mus musculus Q66JT0 555 62324 W77 E S P G P D L W K S V S G P P
Rat Rattus norvegicus Q63802 646 71478 D161 C G V P R A M D D P C S P Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520344 429 47032
Chicken Gallus gallus NP_001026352 641 70947 D99 P A A A P L P D E G D S W E E
Frog Xenopus laevis P47817 555 61670 P75 S P S S D Y S P D P S V G A E
Zebra Danio Brachydanio rerio NP_001032299 527 59094 K71 I P Y A A W K K L R L C D S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54350 609 68790 S100 V R A L R L F S T P A T P K T
Honey Bee Apis mellifera XP_624069 589 66032 S121 R A L R L F D S P A T P K T L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999796 624 68925 N90 S R L H D G E N S I A S P H F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.7 94.3 71.9 N.A. 66.8 43 N.A. 47.7 42.1 52.9 43.5 N.A. 33.5 36.1 N.A. 39.2
Protein Similarity: 100 78.1 95.9 77.7 N.A. 76.5 56.8 N.A. 57.1 57.8 64.9 58.9 N.A. 50.7 52.6 N.A. 55.2
P-Site Identity: 100 0 100 26.6 N.A. 0 6.6 N.A. 0 6.6 20 6.6 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 0 100 33.3 N.A. 0 6.6 N.A. 0 13.3 26.6 13.3 N.A. 26.6 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 16 16 8 8 0 0 0 8 16 0 0 8 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % C
% Asp: 0 0 16 0 16 8 8 16 16 0 8 0 8 0 0 % D
% Glu: 8 0 0 0 0 0 8 0 8 0 0 0 0 8 16 % E
% Phe: 0 0 8 0 0 8 8 0 0 0 0 0 0 0 8 % F
% Gly: 0 8 0 8 0 8 0 0 0 8 0 0 16 0 8 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 16 0 16 0 % H
% Ile: 8 0 0 0 16 0 0 0 0 8 0 0 8 0 0 % I
% Lys: 0 8 0 0 0 0 8 8 8 0 0 0 8 8 16 % K
% Leu: 0 0 16 8 8 31 8 0 8 0 8 0 0 16 8 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 8 31 8 8 24 8 8 8 31 24 0 8 39 8 24 % P
% Gln: 0 0 0 16 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 8 16 0 8 16 0 24 0 0 8 0 0 0 0 0 % R
% Ser: 31 8 8 8 0 0 8 16 8 16 31 39 0 8 0 % S
% Thr: 0 0 0 8 0 0 0 24 8 0 8 8 0 8 8 % T
% Val: 8 0 8 0 0 0 0 0 0 16 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 8 0 0 0 0 8 0 0 % W
% Tyr: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _