KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFPT
All Species:
20.91
Human Site:
T246
Identified Species:
57.5
UniProt:
P0C1Z6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C1Z6
NP_037474.1
253
28278
T246
D
K
L
L
P
Y
P
T
L
A
S
P
A
S
D
Chimpanzee
Pan troglodytes
XP_001174783
244
27186
T237
D
K
L
L
P
Y
P
T
L
A
S
P
A
S
D
Rhesus Macaque
Macaca mulatta
XP_001116861
253
28221
T246
D
K
L
L
P
Y
P
T
L
A
S
P
A
S
D
Dog
Lupus familis
XP_854238
253
28269
T246
D
K
L
L
P
Y
P
T
L
A
S
P
P
F
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3U1J1
259
28935
T252
D
K
L
L
P
Y
P
T
L
A
S
P
P
F
D
Rat
Rattus norvegicus
Q9JMG6
259
28889
T252
D
K
L
L
P
Y
P
T
L
A
S
P
P
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512352
253
28036
G246
D
K
L
L
Q
Y
P
G
L
V
S
P
P
F
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086435
252
28867
K245
D
K
I
L
Q
Y
P
K
F
S
S
P
D
F
D
Zebra Danio
Brachydanio rerio
NP_001154179
186
20727
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
98
95.2
N.A.
86.4
86.4
N.A.
81
N.A.
56.5
42.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.4
98.4
96
N.A.
88.4
88.4
N.A.
84.5
N.A.
69.9
54.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
66.6
N.A.
53.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
66.6
N.A.
66.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
67
0
0
34
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
89
0
0
0
0
0
0
0
0
0
0
0
12
0
89
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
0
0
56
0
% F
% Gly:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
89
0
0
0
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
0
78
89
0
0
0
0
78
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
67
0
89
0
0
0
0
89
45
0
0
% P
% Gln:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
12
89
0
0
34
0
% S
% Thr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
89
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _