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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM86B2
All Species:
7.58
Human Site:
S218
Identified Species:
18.52
UniProt:
P0C5J1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C5J1
NP_001131082.1
330
36771
S218
D
I
T
G
N
L
D
S
P
R
V
T
V
A
Q
Chimpanzee
Pan troglodytes
XP_511218
302
33492
M204
Q
L
D
R
D
V
A
M
V
H
Q
L
S
A
F
Rhesus Macaque
Macaca mulatta
XP_001100213
330
36755
S218
D
I
T
A
N
L
D
S
P
R
V
T
V
A
Q
Dog
Lupus familis
XP_852896
319
34952
W217
V
T
V
A
Q
L
D
W
D
V
V
T
A
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3UZW7
335
36922
S218
H
T
P
I
D
A
G
S
S
K
V
T
V
A
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025798
338
37684
Q227
A
E
G
K
E
Y
Q
Q
P
K
L
V
V
A
E
Frog
Xenopus laevis
NP_001090098
316
35802
N214
D
N
L
M
K
E
K
N
V
K
E
Y
G
E
A
Zebra Danio
Brachydanio rerio
NP_001006058
298
33835
S200
E
L
D
W
E
N
V
S
D
E
Q
L
Q
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573368
319
35261
W216
P
Q
A
E
Q
L
N
W
A
A
V
S
E
F
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P30643
371
42049
V249
A
N
N
N
Q
A
T
V
R
S
L
N
W
C
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
91.5
70.3
N.A.
68.9
N.A.
N.A.
N.A.
52.6
46
42.7
N.A.
24.5
N.A.
24.5
N.A.
Protein Similarity:
100
84.5
94.5
78.4
N.A.
77.3
N.A.
N.A.
N.A.
65.6
63.3
60.6
N.A.
43.3
N.A.
42.8
N.A.
P-Site Identity:
100
6.6
93.3
33.3
N.A.
40
N.A.
N.A.
N.A.
20
6.6
6.6
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
26.6
93.3
33.3
N.A.
53.3
N.A.
N.A.
N.A.
40
20
20
N.A.
26.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
10
20
0
20
10
0
10
10
0
0
10
50
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
30
0
20
0
20
0
30
0
20
0
0
0
0
0
10
% D
% Glu:
10
10
0
10
20
10
0
0
0
10
10
0
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% F
% Gly:
0
0
10
10
0
0
10
0
0
0
0
0
10
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
20
0
10
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
10
10
0
10
0
0
30
0
0
0
0
0
% K
% Leu:
0
20
10
0
0
40
0
0
0
0
20
20
0
0
0
% L
% Met:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
20
10
10
20
10
10
10
0
0
0
10
0
0
0
% N
% Pro:
10
0
10
0
0
0
0
0
30
0
0
0
0
10
10
% P
% Gln:
10
10
0
0
30
0
10
10
0
0
20
0
10
0
40
% Q
% Arg:
0
0
0
10
0
0
0
0
10
20
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
40
10
10
0
10
10
0
0
% S
% Thr:
0
20
20
0
0
0
10
0
0
0
0
40
0
0
0
% T
% Val:
10
0
10
0
0
10
10
10
20
10
50
10
40
0
0
% V
% Trp:
0
0
0
10
0
0
0
20
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _