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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H2AFB1 All Species: 13.94
Human Site: S49 Identified Species: 30.67
UniProt: P0C5Y9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C5Y9 NP_001017990.1 115 12697 S49 G H Y A Q R L S R T A P V Y L
Chimpanzee Pan troglodytes XP_001145032 115 12609 S49 G Q Y A Q R L S R T A P V Y L
Rhesus Macaque Macaca mulatta XP_001091351 115 12659 S49 G H Y A Q R L S P T A P V Y L
Dog Lupus familis XP_855480 163 17781 G97 G R Y A K R L G A S A P I F L
Cat Felis silvestris
Mouse Mus musculus P27661 143 15124 T77 A A R D N K K T R I I P R H L
Rat Rattus norvegicus P02262 130 14059 P49 E R V G A G A P V Y L A A V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512371 142 15010 T77 A A R D N K K T R I I P R H L
Chicken Gallus gallus P02263 129 13922 P49 E R V G A G A P V Y L A A V L
Frog Xenopus laevis P06897 130 13948 P49 E R V G A G A P V Y L A A V L
Zebra Danio Brachydanio rerio Q7ZUY3 142 14983 T77 A A R D N K K T R I I P R H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P16886 126 13432 P49 Q R V G A G A P V Y L A A V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 86.9 42.3 N.A. 36.3 37.6 N.A. 36.6 37.2 38.4 34.5 N.A. N.A. N.A. N.A. 39.6
Protein Similarity: 100 96.5 89.5 52.1 N.A. 53.1 54.6 N.A. 52.1 55 55.3 51.4 N.A. N.A. N.A. N.A. 55.5
P-Site Identity: 100 93.3 93.3 53.3 N.A. 20 6.6 N.A. 20 6.6 6.6 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 93.3 93.3 80 N.A. 40 6.6 N.A. 40 6.6 6.6 40 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 28 0 37 37 0 37 0 10 0 37 37 37 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 28 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 37 0 0 37 0 37 0 10 0 0 0 0 0 0 0 % G
% His: 0 19 0 0 0 0 0 0 0 0 0 0 0 28 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 28 28 0 10 0 0 % I
% Lys: 0 0 0 0 10 28 28 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 37 0 0 0 37 0 0 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 28 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 37 10 0 0 64 0 0 0 % P
% Gln: 10 10 0 0 28 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 46 28 0 0 37 0 0 46 0 0 0 28 0 0 % R
% Ser: 0 0 0 0 0 0 0 28 0 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 28 0 28 0 0 0 0 0 % T
% Val: 0 0 37 0 0 0 0 0 37 0 0 0 28 37 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 37 0 0 0 0 0 0 37 0 0 0 28 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _