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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 28.48
Human Site: S112 Identified Species: 44.76
UniProt: P0C6E5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C6E5 XP_001715282 187 21143 S112 E F C P K S K S T N P G I P I
Chimpanzee Pan troglodytes Q9N1Q7 215 24747 G144 E Y R P K I K G E H P G L S I
Rhesus Macaque Macaca mulatta XP_001091672 201 23091 S113 E F R P K I K S T N P G I S I
Dog Lupus familis XP_538194 201 23063 S113 E F R P K I K S T N P G I S I
Cat Felis silvestris
Mouse Mus musculus O54879 200 22991 S113 E F R P K I K S T N P G I S I
Rat Rattus norvegicus P52925 210 24140 S115 E H R P K I K S E H P G L S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509199 201 22939 S113 E F R P K I K S T N P G I S I
Chicken Gallus gallus P40618 202 23052 S113 E F R P K I K S T N P G I S I
Frog Xenopus laevis NP_001089163 201 23278 S113 E F R P K I K S T N P G I S I
Zebra Danio Brachydanio rerio NP_001116308 213 24538 A112 E H R P Q I K A Q Y P S L G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24537 393 44916 A291 D E R N K V K A L N P E F G V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09390 235 27301 A155 D K R P E I Q A G H P D W K V
Sea Urchin Strong. purpuratus P40644 200 22815 S120 E N R A A I K S V H P N W S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P11633 99 11557 S47 E N R D I V R S E N P D V T F
Red Bread Mold Neurospora crassa Q7S045 103 11590 V51 V R E E N P G V S F G Q V G K
Conservation
Percent
Protein Identity: 100 46 84.5 83.5 N.A. 83 64.7 N.A. 82.5 80.6 76.1 60 N.A. 25.9 N.A. 32.3 42.5
Protein Similarity: 100 58.5 89 88 N.A. 89.5 74.7 N.A. 87 85.6 84 72.7 N.A. 36.3 N.A. 45.5 57.5
P-Site Identity: 100 46.6 80 80 N.A. 80 53.3 N.A. 80 80 80 33.3 N.A. 26.6 N.A. 13.3 26.6
P-Site Similarity: 100 66.6 80 80 N.A. 80 66.6 N.A. 80 80 80 53.3 N.A. 46.6 N.A. 53.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.3 22.4
Protein Similarity: N.A. N.A. N.A. N.A. 33.6 35.2
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 40 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 0 0 20 0 0 0 0 0 0 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 0 7 0 0 0 0 0 0 0 14 0 0 0 % D
% Glu: 80 7 7 7 7 0 0 0 20 0 0 7 0 0 0 % E
% Phe: 0 47 0 0 0 0 0 0 0 7 0 0 7 0 7 % F
% Gly: 0 0 0 0 0 0 7 7 7 0 7 60 0 20 0 % G
% His: 0 14 0 0 0 0 0 0 0 27 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 74 0 0 0 0 0 0 47 0 67 % I
% Lys: 0 7 0 0 67 0 80 0 0 0 0 0 0 7 7 % K
% Leu: 0 0 0 0 0 0 0 0 7 0 0 0 20 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 14 0 7 7 0 0 0 0 60 0 7 0 0 0 % N
% Pro: 0 0 0 74 0 7 0 0 0 0 94 0 0 7 0 % P
% Gln: 0 0 0 0 7 0 7 0 7 0 0 7 0 0 0 % Q
% Arg: 0 7 87 0 0 0 7 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 7 0 67 7 0 0 7 0 60 0 % S
% Thr: 0 0 0 0 0 0 0 0 47 0 0 0 0 7 0 % T
% Val: 7 0 0 0 0 14 0 7 7 0 0 0 14 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _