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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 46.06
Human Site: S46 Identified Species: 72.38
UniProt: P0C6E5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C6E5 XP_001715282 187 21143 S46 A E F S K K C S E R W K T M S
Chimpanzee Pan troglodytes Q9N1Q7 215 24747 S75 S E F L K K R S E M W K T I F
Rhesus Macaque Macaca mulatta XP_001091672 201 23091 S46 A E F S K K C S E R W K T M S
Dog Lupus familis XP_538194 201 23063 S46 A E F S K K C S E R W K T M S
Cat Felis silvestris
Mouse Mus musculus O54879 200 22991 S46 A E F S K K C S E R W K T M S
Rat Rattus norvegicus P52925 210 24140 S46 A E F S K K C S E R W K T M S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509199 201 22939 S46 A E F S K K C S E R W K T M S
Chicken Gallus gallus P40618 202 23052 S46 A E F S K K C S E R W K T M S
Frog Xenopus laevis NP_001089163 201 23278 S46 A E F S K K C S E R W R S M S
Zebra Danio Brachydanio rerio NP_001116308 213 24538 S46 S E F S K R C S G R W K A M T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24537 393 44916 A216 A E F S R K C A E R W K T M V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09390 235 27301 S82 T E I S K K C S E K W K T M V
Sea Urchin Strong. purpuratus P40644 200 22815 S48 A E F S K D C S A R W K A L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P11633 99 11557
Red Bread Mold Neurospora crassa Q7S045 103 11590
Conservation
Percent
Protein Identity: 100 46 84.5 83.5 N.A. 83 64.7 N.A. 82.5 80.6 76.1 60 N.A. 25.9 N.A. 32.3 42.5
Protein Similarity: 100 58.5 89 88 N.A. 89.5 74.7 N.A. 87 85.6 84 72.7 N.A. 36.3 N.A. 45.5 57.5
P-Site Identity: 100 60 100 100 N.A. 100 100 N.A. 100 100 86.6 66.6 N.A. 80 N.A. 73.3 66.6
P-Site Similarity: 100 73.3 100 100 N.A. 100 100 N.A. 100 100 100 86.6 N.A. 93.3 N.A. 80 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.3 22.4
Protein Similarity: N.A. N.A. N.A. N.A. 33.6 35.2
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 67 0 0 0 0 0 0 7 7 0 0 0 14 0 0 % A
% Cys: 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 87 0 0 0 0 0 0 74 0 0 0 0 0 7 % E
% Phe: 0 0 80 0 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % I
% Lys: 0 0 0 0 80 74 0 0 0 7 0 80 0 0 0 % K
% Leu: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 74 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 7 7 7 0 0 74 0 7 0 0 0 % R
% Ser: 14 0 0 80 0 0 0 80 0 0 0 0 7 0 54 % S
% Thr: 7 0 0 0 0 0 0 0 0 0 0 0 67 0 7 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 87 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _