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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSM4
All Species:
35.15
Human Site:
T218
Identified Species:
85.93
UniProt:
P0C7M7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C7M7
NP_001073923.1
580
65703
T218
E
E
H
S
C
V
E
T
G
S
Q
E
P
M
T
Chimpanzee
Pan troglodytes
XP_508984
580
65571
T218
E
E
H
S
C
V
E
T
G
S
Q
E
P
M
T
Rhesus Macaque
Macaca mulatta
XP_001118353
879
98865
T517
E
E
H
S
C
V
E
T
R
S
Q
E
P
M
T
Dog
Lupus familis
XP_536948
583
65068
T221
S
E
H
N
C
V
E
T
G
S
Q
E
P
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80W40
580
65409
T218
E
E
H
N
C
V
E
T
G
S
Q
E
P
M
A
Rat
Rattus norvegicus
Q7TN78
580
65298
T218
E
E
H
N
C
V
Q
T
G
S
Q
E
P
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508475
585
66369
T224
D
D
H
S
C
V
K
T
R
H
N
E
A
M
T
Chicken
Gallus gallus
XP_424596
618
69154
T256
A
D
H
K
C
V
K
T
R
N
D
D
P
M
L
Frog
Xenopus laevis
NP_001086370
584
65403
T219
D
K
H
I
C
V
K
T
K
S
S
D
P
M
T
Zebra Danio
Brachydanio rerio
NP_001104706
591
66900
T227
D
D
H
V
C
V
D
T
S
S
E
E
P
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
63.1
84.7
N.A.
86.7
86.2
N.A.
63.2
59.2
59.5
56.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
64.2
90.5
N.A.
92.4
92.5
N.A.
78.4
74.9
77.2
72.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
86.6
80
N.A.
53.3
40
53.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
73.3
66.6
80
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
30
% A
% Cys:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
30
0
0
0
0
10
0
0
0
10
20
0
0
0
% D
% Glu:
50
60
0
0
0
0
50
0
0
0
10
80
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% G
% His:
0
0
100
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
0
0
30
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% M
% Asn:
0
0
0
30
0
0
0
0
0
10
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
90
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
60
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% R
% Ser:
10
0
0
40
0
0
0
0
10
80
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
60
% T
% Val:
0
0
0
10
0
100
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _