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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UQCRFSL1
All Species:
4.55
Human Site:
S166
Identified Species:
6.67
UniProt:
P0C7P4
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.6
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C7P4
NP_005994
283
30815
S166
A
K
I
E
I
K
L
S
D
I
P
E
G
K
N
Chimpanzee
Pan troglodytes
Q69BK5
274
29619
K172
M
A
F
K
W
R
G
K
P
L
F
V
R
H
R
Rhesus Macaque
Macaca mulatta
XP_001101202
274
29734
K172
M
T
F
K
W
R
G
K
P
L
F
V
R
H
R
Dog
Lupus familis
XP_533711
274
29434
R170
K
N
M
A
F
K
W
R
G
K
P
L
F
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR68
274
29349
R170
K
N
M
A
F
K
W
R
G
K
P
L
F
V
R
Rat
Rattus norvegicus
P20788
274
29427
R170
K
N
M
A
F
K
W
R
G
K
P
L
F
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506483
366
39594
S249
S
K
I
E
I
K
L
S
D
I
P
E
G
K
N
Chicken
Gallus gallus
Q5ZLR5
272
29368
K170
V
A
F
K
W
R
G
K
P
L
F
V
R
H
R
Frog
Xenopus laevis
NP_001090500
273
29267
K171
M
A
F
K
W
R
G
K
P
L
F
V
R
H
R
Zebra Danio
Brachydanio rerio
NP_001096664
273
29695
R169
K
N
M
T
F
K
W
R
G
K
P
L
F
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722715
230
24854
R133
R
G
K
P
L
F
I
R
H
R
T
A
A
E
I
Honey Bee
Apis mellifera
XP_394657
274
29793
F167
P
E
G
K
S
A
V
F
K
W
R
G
K
P
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780127
274
29985
P173
T
F
K
W
R
G
K
P
L
F
V
R
H
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49727
273
29817
V166
E
P
G
T
T
V
T
V
K
W
R
G
K
P
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P08067
215
23346
I118
W
Q
G
K
P
V
F
I
R
H
R
T
P
H
E
Red Bread Mold
Neurospora crassa
P07056
231
24752
I133
W
R
G
K
P
V
F
I
R
H
R
T
P
A
E
Conservation
Percent
Protein Identity:
100
95
90.4
83.7
N.A.
85.1
86.2
N.A.
57
71.3
72
66.7
N.A.
52.6
50.5
N.A.
53.7
Protein Similarity:
100
96.4
94.3
90.1
N.A.
90.8
91.8
N.A.
64.4
80.9
81.2
77.7
N.A.
65.3
68.1
N.A.
67.8
P-Site Identity:
100
0
0
13.3
N.A.
13.3
13.3
N.A.
93.3
0
0
13.3
N.A.
0
0
N.A.
0
P-Site Similarity:
100
20
20
20
N.A.
20
20
N.A.
100
20
20
20
N.A.
20
20
N.A.
6.6
Percent
Protein Identity:
N.A.
40.6
N.A.
N.A.
43.1
42.7
Protein Similarity:
N.A.
57.2
N.A.
N.A.
59
59
P-Site Identity:
N.A.
0
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
0
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
19
0
19
0
7
0
0
0
0
0
7
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% D
% Glu:
7
7
0
13
0
0
0
0
0
0
0
13
0
7
13
% E
% Phe:
0
7
25
0
25
7
13
7
0
7
25
0
25
0
0
% F
% Gly:
0
7
25
0
0
7
25
0
25
0
0
13
13
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
13
0
0
7
32
0
% H
% Ile:
0
0
13
0
13
0
7
13
0
13
0
0
0
0
13
% I
% Lys:
25
13
13
44
0
38
7
25
13
25
0
0
13
13
0
% K
% Leu:
0
0
0
0
7
0
13
0
7
25
0
25
0
0
0
% L
% Met:
19
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
13
% N
% Pro:
7
7
0
7
13
0
0
7
25
0
38
0
13
13
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
7
0
0
7
25
0
32
13
7
25
7
25
7
50
% R
% Ser:
7
0
0
0
7
0
0
13
0
0
0
0
0
0
0
% S
% Thr:
7
7
0
13
7
0
7
0
0
0
7
13
0
0
7
% T
% Val:
7
0
0
0
0
19
7
7
0
0
7
25
0
25
7
% V
% Trp:
13
0
0
7
25
0
25
0
0
13
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _