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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATXN1L All Species: 20.3
Human Site: S589 Identified Species: 44.67
UniProt: P0C7T5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C7T5 NP_001131147.1 689 73306 S589 L Q S L N S N S V S Q A S C A
Chimpanzee Pan troglodytes XP_511093 587 62648 V488 Q S L N S N S V S Q A S C A P
Rhesus Macaque Macaca mulatta XP_001098366 689 73153 S589 L Q S L N S N S V S Q A S C A
Dog Lupus familis XP_546845 687 73367 S587 L Q S L N S N S V S Q A S C A
Cat Felis silvestris
Mouse Mus musculus P0C7T6 687 73356 S587 L Q S L N S N S V S Q A S C A
Rat Rattus norvegicus Q63540 789 83482 S668 L K N L K N G S V K K G Q P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509567 686 71870 S581 L Q S L N S N S V S Q A G C S
Chicken Gallus gallus XP_425139 690 74081 F585 L Q S M N G N F A S Q A N Y P
Frog Xenopus laevis NP_001121333 691 74939 D590 L Q S A V K N D A S T V S C T
Zebra Danio Brachydanio rerio XP_001333781 765 81955 Q616 L Q Q Q A A S Q Q K P P Q Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190485 925 98737 G768 V I E N G K Q G L K E D S E A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85 97.8 96 N.A. 93.6 28.7 N.A. 76.1 65.3 50.9 35.1 N.A. N.A. N.A. N.A. 24.2
Protein Similarity: 100 85.1 98.2 97.5 N.A. 95.7 42.8 N.A. 81.7 74.6 63.8 47.9 N.A. N.A. N.A. N.A. 36.4
P-Site Identity: 100 0 100 100 N.A. 100 26.6 N.A. 86.6 53.3 46.6 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 53.3 N.A. 93.3 66.6 46.6 26.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 10 0 0 19 0 10 55 0 10 46 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 55 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 10 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 10 10 10 0 0 0 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 10 19 0 0 0 28 10 0 0 0 0 % K
% Leu: 82 0 10 55 0 0 0 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 19 55 19 64 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 10 10 0 10 19 % P
% Gln: 10 73 10 10 0 0 10 10 10 10 55 0 19 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 64 0 10 46 19 55 10 64 0 10 55 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % T
% Val: 10 0 0 0 10 0 0 10 55 0 0 10 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _