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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF8L2
All Species:
18.18
Human Site:
S135
Identified Species:
40
UniProt:
P0C7V8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C7V8
NP_001130005
602
67911
S135
G
G
N
H
E
Q
Y
S
L
E
E
D
Q
A
L
Chimpanzee
Pan troglodytes
XP_520989
616
69455
S149
G
G
N
H
E
Q
Y
S
F
E
E
D
Q
A
L
Rhesus Macaque
Macaca mulatta
XP_001093503
626
70614
L159
G
A
N
H
E
Q
Y
L
L
E
E
D
R
A
L
Dog
Lupus familis
XP_536129
596
66580
S128
R
A
N
R
D
Q
D
S
S
D
D
E
R
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8N7N5
591
66013
S123
R
A
S
R
D
Q
D
S
S
D
D
E
R
A
L
Rat
Rattus norvegicus
Q5U2M6
591
66137
S123
R
A
S
R
D
Q
D
S
S
D
D
E
R
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRH1
601
67089
S132
R
A
N
R
D
Q
E
S
S
D
E
E
R
A
L
Zebra Danio
Brachydanio rerio
XP_001346262
607
66784
E140
N
E
E
D
D
D
V
E
E
E
D
E
Q
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647657
748
83317
T231
S
L
S
S
E
D
E
T
T
T
E
V
E
N
L
Honey Bee
Apis mellifera
XP_392352
669
75650
E202
N
Y
S
N
F
G
M
E
Q
T
S
S
E
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785904
416
46675
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.4
90.2
69.7
N.A.
67.9
68.7
N.A.
N.A.
N.A.
63.2
52
N.A.
30.7
35.4
N.A.
39.8
Protein Similarity:
100
96.5
93.1
80.4
N.A.
80.2
79.9
N.A.
N.A.
N.A.
76.7
67
N.A.
47.5
56.2
N.A.
51.5
P-Site Identity:
100
93.3
80
33.3
N.A.
26.6
26.6
N.A.
N.A.
N.A.
40
20
N.A.
20
0
N.A.
0
P-Site Similarity:
100
93.3
86.6
66.6
N.A.
66.6
66.6
N.A.
N.A.
N.A.
66.6
46.6
N.A.
40
20
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
46
0
0
0
0
0
0
0
0
0
0
0
73
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
46
19
28
0
0
37
37
28
0
0
0
% D
% Glu:
0
10
10
0
37
0
19
19
10
37
46
46
19
10
10
% E
% Phe:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
28
19
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
10
19
0
0
0
0
0
73
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% M
% Asn:
19
0
46
10
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
64
0
0
10
0
0
0
28
0
0
% Q
% Arg:
37
0
0
37
0
0
0
0
0
0
0
0
46
0
0
% R
% Ser:
10
0
37
10
0
0
0
55
37
0
10
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
10
19
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
28
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _