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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF8L2
All Species:
40
Human Site:
S411
Identified Species:
88
UniProt:
P0C7V8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C7V8
NP_001130005
602
67911
S411
D
G
T
E
L
L
A
S
Y
N
D
D
D
I
Y
Chimpanzee
Pan troglodytes
XP_520989
616
69455
S425
D
G
T
E
L
L
A
S
Y
N
D
D
D
I
Y
Rhesus Macaque
Macaca mulatta
XP_001093503
626
70614
S435
D
G
T
E
L
L
A
S
Y
N
D
E
D
I
Y
Dog
Lupus familis
XP_536129
596
66580
S404
D
G
T
E
L
L
A
S
Y
N
D
E
D
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8N7N5
591
66013
S399
D
G
T
E
L
L
A
S
Y
N
D
E
D
I
Y
Rat
Rattus norvegicus
Q5U2M6
591
66137
S399
D
G
T
E
L
L
A
S
Y
N
D
E
D
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRH1
601
67089
S408
D
G
S
E
L
L
A
S
Y
N
D
E
D
I
Y
Zebra Danio
Brachydanio rerio
XP_001346262
607
66784
S417
D
G
T
E
L
L
A
S
Y
N
D
E
D
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647657
748
83317
S535
S
G
S
E
I
L
A
S
Y
S
D
A
G
I
Y
Honey Bee
Apis mellifera
XP_392352
669
75650
S467
D
G
T
E
V
L
A
S
Y
N
D
E
D
I
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785904
416
46675
E228
L
Y
S
Y
N
G
Q
E
I
L
A
S
Y
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.4
90.2
69.7
N.A.
67.9
68.7
N.A.
N.A.
N.A.
63.2
52
N.A.
30.7
35.4
N.A.
39.8
Protein Similarity:
100
96.5
93.1
80.4
N.A.
80.2
79.9
N.A.
N.A.
N.A.
76.7
67
N.A.
47.5
56.2
N.A.
51.5
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
86.6
93.3
N.A.
60
86.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
100
100
N.A.
80
100
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
91
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
82
0
0
0
0
0
0
0
0
0
91
19
82
0
10
% D
% Glu:
0
0
0
91
0
0
0
10
0
0
0
64
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
91
0
0
0
10
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
10
0
0
0
0
91
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
73
91
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
82
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
28
0
0
0
0
91
0
10
0
10
0
0
0
% S
% Thr:
0
0
73
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
0
0
0
91
0
0
0
10
0
91
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _