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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF8L2
All Species:
38.48
Human Site:
T442
Identified Species:
84.67
UniProt:
P0C7V8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C7V8
NP_001130005
602
67911
T442
K
G
H
R
N
N
T
T
V
K
G
V
N
F
Y
Chimpanzee
Pan troglodytes
XP_520989
616
69455
T456
K
G
H
R
N
N
T
T
V
K
G
V
N
F
Y
Rhesus Macaque
Macaca mulatta
XP_001093503
626
70614
T466
K
G
H
R
N
N
T
T
V
K
G
V
N
F
Y
Dog
Lupus familis
XP_536129
596
66580
T435
K
G
H
R
N
N
A
T
V
K
G
V
N
F
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8N7N5
591
66013
T430
K
G
H
R
N
N
A
T
V
K
G
V
N
F
Y
Rat
Rattus norvegicus
Q5U2M6
591
66137
T430
K
G
H
R
N
N
A
T
V
K
G
V
N
F
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRH1
601
67089
T439
K
G
H
R
N
N
A
T
V
K
G
V
N
F
Y
Zebra Danio
Brachydanio rerio
XP_001346262
607
66784
T448
K
G
H
R
N
N
A
T
V
K
G
V
N
F
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647657
748
83317
T566
K
G
H
I
N
S
R
T
I
K
G
V
N
F
F
Honey Bee
Apis mellifera
XP_392352
669
75650
T498
E
G
H
R
N
N
A
T
V
K
G
V
N
F
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785904
416
46675
R259
T
H
A
Y
R
G
H
R
N
N
A
T
V
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.4
90.2
69.7
N.A.
67.9
68.7
N.A.
N.A.
N.A.
63.2
52
N.A.
30.7
35.4
N.A.
39.8
Protein Similarity:
100
96.5
93.1
80.4
N.A.
80.2
79.9
N.A.
N.A.
N.A.
76.7
67
N.A.
47.5
56.2
N.A.
51.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
93.3
N.A.
66.6
80
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
93.3
N.A.
86.6
93.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
55
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
91
19
% F
% Gly:
0
91
0
0
0
10
0
0
0
0
91
0
0
0
10
% G
% His:
0
10
91
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
82
0
0
0
0
0
0
0
0
91
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
91
82
0
0
10
10
0
0
91
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
82
10
0
10
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
28
91
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
82
0
0
91
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
73
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _