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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCAF8L2 All Species: 14.24
Human Site: Y193 Identified Species: 31.33
UniProt: P0C7V8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C7V8 NP_001130005 602 67911 Y193 V Q R F R L Q Y R L A D H V G
Chimpanzee Pan troglodytes XP_520989 616 69455 Y207 V Q R F R L Q Y R L A D H V G
Rhesus Macaque Macaca mulatta XP_001093503 626 70614 Y217 V Q R F R L Q Y R L A D H V G
Dog Lupus familis XP_536129 596 66580 H186 V Q R F R L Q H G L E G H T G
Cat Felis silvestris
Mouse Mus musculus Q8N7N5 591 66013 H181 V Q R F R L Q H G L E G H T G
Rat Rattus norvegicus Q5U2M6 591 66137 H181 V Q R F R L Q H G L E G H T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NRH1 601 67089 H190 V Q R F H L L H G L D G H S G
Zebra Danio Brachydanio rerio XP_001346262 607 66784 G199 V Q R L E L Q G R L E R H T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647657 748 83317 S320 V E Q M T L L S S L N V H H G
Honey Bee Apis mellifera XP_392352 669 75650 Y260 V E H F E L M Y K L K E H E G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785904 416 46675 F28 G C V N T L H F N P A G D L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.4 90.2 69.7 N.A. 67.9 68.7 N.A. N.A. N.A. 63.2 52 N.A. 30.7 35.4 N.A. 39.8
Protein Similarity: 100 96.5 93.1 80.4 N.A. 80.2 79.9 N.A. N.A. N.A. 76.7 67 N.A. 47.5 56.2 N.A. 51.5
P-Site Identity: 100 100 100 66.6 N.A. 66.6 66.6 N.A. N.A. N.A. 53.3 60 N.A. 33.3 46.6 N.A. 13.3
P-Site Similarity: 100 100 100 73.3 N.A. 73.3 73.3 N.A. N.A. N.A. 60 60 N.A. 46.6 66.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 37 0 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 28 10 0 0 % D
% Glu: 0 19 0 0 19 0 0 0 0 0 37 10 0 10 0 % E
% Phe: 0 0 0 73 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 10 37 0 0 46 0 0 91 % G
% His: 0 0 10 0 10 0 10 37 0 0 0 0 91 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % K
% Leu: 0 0 0 10 0 100 19 0 0 91 0 0 0 10 10 % L
% Met: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 10 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 73 10 0 0 0 64 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 73 0 55 0 0 0 37 0 0 10 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 10 10 0 0 0 0 10 0 % S
% Thr: 0 0 0 0 19 0 0 0 0 0 0 0 0 37 0 % T
% Val: 91 0 10 0 0 0 0 0 0 0 0 10 0 28 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 37 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _