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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP14L
All Species:
7.27
Human Site:
S122
Identified Species:
22.86
UniProt:
P0CB46
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0CB46
XP_001717694
183
20061
S122
A
Y
R
D
D
K
G
S
D
F
I
Q
T
L
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090736
470
51135
S409
A
Y
R
D
D
K
G
S
D
F
I
Q
T
L
V
Dog
Lupus familis
XP_853312
452
49198
T396
K
G
S
D
F
I
Q
T
L
A
E
V
L
R
A
Cat
Felis silvestris
Mouse
Mus musculus
O89094
257
29440
M106
L
K
G
E
D
E
K
M
V
R
L
E
D
L
F
Rat
Rattus norvegicus
O35397
277
31537
D166
D
V
V
D
H
Q
T
D
K
L
D
D
N
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02002
323
35908
G249
S
W
R
N
I
N
N
G
S
W
Y
M
Q
S
L
Honey Bee
Apis mellifera
XP_395697
298
33761
S227
W
R
N
T
T
R
G
S
W
F
I
Q
A
L
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792621
282
31791
G218
S
W
R
N
S
E
R
G
S
W
F
I
Q
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
36.5
27.8
N.A.
26.4
21.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
22.6
22.1
N.A.
22.7
Protein Similarity:
100
N.A.
38.2
33.1
N.A.
39.6
36
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
32.5
32.2
N.A.
35.1
P-Site Identity:
100
N.A.
100
6.6
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
40
N.A.
6.6
P-Site Similarity:
100
N.A.
100
13.3
N.A.
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
46.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
0
0
0
0
0
13
0
0
13
13
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% C
% Asp:
13
0
0
50
38
0
0
13
25
0
13
13
13
0
0
% D
% Glu:
0
0
0
13
0
25
0
0
0
0
13
13
0
0
0
% E
% Phe:
0
0
0
0
13
0
0
0
0
38
13
0
0
0
13
% F
% Gly:
0
13
13
0
0
0
38
25
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
13
0
0
0
0
38
13
0
0
0
% I
% Lys:
13
13
0
0
0
25
13
0
13
0
0
0
0
0
0
% K
% Leu:
13
0
0
0
0
0
0
0
13
13
13
0
13
50
25
% L
% Met:
0
0
0
0
0
0
0
13
0
0
0
13
0
0
0
% M
% Asn:
0
0
13
25
0
13
13
0
0
0
0
0
13
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
13
13
0
0
0
0
38
25
0
0
% Q
% Arg:
0
13
50
0
0
13
13
0
0
13
0
0
0
13
0
% R
% Ser:
25
0
13
0
13
0
0
38
25
0
0
0
0
13
0
% S
% Thr:
0
0
0
13
13
0
13
13
0
0
0
0
25
0
13
% T
% Val:
0
13
13
0
0
0
0
0
13
0
0
13
0
13
25
% V
% Trp:
13
25
0
0
0
0
0
0
13
25
0
0
0
0
0
% W
% Tyr:
0
25
0
0
0
0
0
0
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _