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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP14L
All Species:
6.06
Human Site:
S28
Identified Species:
19.05
UniProt:
P0CB46
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0CB46
XP_001717694
183
20061
S28
E
A
L
M
Q
E
L
S
R
C
Q
V
L
Q
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090736
470
51135
S315
E
A
L
M
Q
E
L
S
R
C
R
V
L
W
G
Dog
Lupus familis
XP_853312
452
49198
N302
E
A
L
V
Q
E
L
N
R
C
R
A
L
W
G
Cat
Felis silvestris
Mouse
Mus musculus
O89094
257
29440
S19
Q
E
E
R
Y
D
M
S
G
A
R
L
A
L
T
Rat
Rattus norvegicus
O35397
277
31537
K69
S
E
L
G
F
E
V
K
C
F
N
D
L
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02002
323
35908
K125
V
S
V
H
K
D
C
K
L
R
D
I
L
K
H
Honey Bee
Apis mellifera
XP_395697
298
33761
E112
R
D
I
V
K
N
L
E
R
V
A
N
M
D
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792621
282
31791
R66
Q
Q
M
I
E
Q
L
R
R
H
N
H
T
Q
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
36.5
27.8
N.A.
26.4
21.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
22.6
22.1
N.A.
22.7
Protein Similarity:
100
N.A.
38.2
33.1
N.A.
39.6
36
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
32.5
32.2
N.A.
35.1
P-Site Identity:
100
N.A.
86.6
66.6
N.A.
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
13.3
N.A.
20
P-Site Similarity:
100
N.A.
93.3
86.6
N.A.
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
40
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
38
0
0
0
0
0
0
0
13
13
13
13
0
13
% A
% Cys:
0
0
0
0
0
0
13
0
13
38
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
25
0
0
0
0
13
13
0
13
0
% D
% Glu:
38
25
13
0
13
50
0
13
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
13
0
0
0
0
13
0
0
0
0
13
% F
% Gly:
0
0
0
13
0
0
0
0
13
0
0
0
0
0
38
% G
% His:
0
0
0
13
0
0
0
0
0
13
0
13
0
0
25
% H
% Ile:
0
0
13
13
0
0
0
0
0
0
0
13
0
0
0
% I
% Lys:
0
0
0
0
25
0
0
25
0
0
0
0
0
13
0
% K
% Leu:
0
0
50
0
0
0
63
0
13
0
0
13
63
13
0
% L
% Met:
0
0
13
25
0
0
13
0
0
0
0
0
13
0
0
% M
% Asn:
0
0
0
0
0
13
0
13
0
0
25
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
25
13
0
0
38
13
0
0
0
0
13
0
0
25
0
% Q
% Arg:
13
0
0
13
0
0
0
13
63
13
38
0
0
13
0
% R
% Ser:
13
13
0
0
0
0
0
38
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
13
% T
% Val:
13
0
13
25
0
0
13
0
0
13
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _