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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP14L
All Species:
4.55
Human Site:
Y116
Identified Species:
14.29
UniProt:
P0CB46
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0CB46
XP_001717694
183
20061
Y116
A
A
E
G
Y
V
A
Y
R
D
D
K
G
S
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090736
470
51135
Y403
A
A
E
G
Y
V
A
Y
R
D
D
K
G
S
D
Dog
Lupus familis
XP_853312
452
49198
G390
V
A
Y
R
D
E
K
G
S
D
F
I
Q
T
L
Cat
Felis silvestris
Mouse
Mus musculus
O89094
257
29440
K100
H
G
E
E
G
L
L
K
G
E
D
E
K
M
V
Rat
Rattus norvegicus
O35397
277
31537
V160
V
P
L
V
P
L
D
V
V
D
H
Q
T
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02002
323
35908
W243
T
I
P
G
Y
F
S
W
R
N
I
N
N
G
S
Honey Bee
Apis mellifera
XP_395697
298
33761
R221
I
P
G
Y
Y
S
W
R
N
T
T
R
G
S
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792621
282
31791
W212
T
V
P
G
F
V
S
W
R
N
S
E
R
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
36.5
27.8
N.A.
26.4
21.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
22.6
22.1
N.A.
22.7
Protein Similarity:
100
N.A.
38.2
33.1
N.A.
39.6
36
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
32.5
32.2
N.A.
35.1
P-Site Identity:
100
N.A.
100
13.3
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
20
N.A.
20
P-Site Similarity:
100
N.A.
100
20
N.A.
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
26.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
38
0
0
0
0
25
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
13
0
13
0
0
50
38
0
0
13
25
% D
% Glu:
0
0
38
13
0
13
0
0
0
13
0
25
0
0
0
% E
% Phe:
0
0
0
0
13
13
0
0
0
0
13
0
0
0
0
% F
% Gly:
0
13
13
50
13
0
0
13
13
0
0
0
38
25
0
% G
% His:
13
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
13
13
0
0
0
0
0
0
0
0
13
13
0
0
0
% I
% Lys:
0
0
0
0
0
0
13
13
0
0
0
25
13
0
13
% K
% Leu:
0
0
13
0
0
25
13
0
0
0
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
25
0
13
13
0
0
% N
% Pro:
0
25
25
0
13
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
13
13
0
0
% Q
% Arg:
0
0
0
13
0
0
0
13
50
0
0
13
13
0
0
% R
% Ser:
0
0
0
0
0
13
25
0
13
0
13
0
0
38
25
% S
% Thr:
25
0
0
0
0
0
0
0
0
13
13
0
13
13
0
% T
% Val:
25
13
0
13
0
38
0
13
13
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
13
25
0
0
0
0
0
0
13
% W
% Tyr:
0
0
13
13
50
0
0
25
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _