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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HKR1
All Species:
17.27
Human Site:
S548
Identified Species:
76
UniProt:
P10072
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10072
NP_861451.1
659
75128
S548
I
S
H
Q
R
T
H
S
G
E
K
P
F
M
C
Chimpanzee
Pan troglodytes
XP_512624
737
83433
S626
I
S
H
Q
R
T
H
S
G
E
K
P
F
M
C
Rhesus Macaque
Macaca mulatta
XP_001117982
554
63404
H468
L
V
S
H
Q
R
T
H
S
G
E
K
P
F
M
Dog
Lupus familis
XP_541656
1223
140528
S594
I
A
H
Q
R
T
H
S
G
E
K
P
F
I
C
Cat
Felis silvestris
Mouse
Mus musculus
Q96EQ9
843
97346
T560
I
Q
H
Q
R
T
H
T
G
E
K
P
Y
V
C
Rat
Rattus norvegicus
XP_001057444
729
82102
T588
I
G
H
Q
K
T
H
T
G
E
K
P
Y
A
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
78
43.2
N.A.
35.4
38.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
87.2
81.1
47.2
N.A.
50.6
53.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
86.6
N.A.
73.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
93.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
0
0
0
0
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
84
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
84
17
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
50
17
0
% F
% Gly:
0
17
0
0
0
0
0
0
84
17
0
0
0
0
0
% G
% His:
0
0
84
17
0
0
84
17
0
0
0
0
0
0
0
% H
% Ile:
84
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% I
% Lys:
0
0
0
0
17
0
0
0
0
0
84
17
0
0
0
% K
% Leu:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
17
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
84
17
0
0
% P
% Gln:
0
17
0
84
17
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
67
17
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
34
17
0
0
0
0
50
17
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
84
17
34
0
0
0
0
0
0
0
% T
% Val:
0
17
0
0
0
0
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _