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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLI4
All Species:
8.79
Human Site:
S277
Identified Species:
38.67
UniProt:
P10075
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10075
NP_612474.1
376
41145
S277
G
E
C
G
Q
A
F
S
Q
S
S
N
L
V
R
Chimpanzee
Pan troglodytes
A2T759
682
76399
N583
N
Q
C
G
K
A
F
N
R
S
S
N
L
I
H
Rhesus Macaque
Macaca mulatta
XP_001095941
719
76822
K620
E
S
C
G
K
S
F
K
Y
N
S
L
L
L
K
Dog
Lupus familis
XP_539196
617
70341
S265
G
E
C
G
Q
A
F
S
Q
S
S
N
L
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNU6
535
59854
V408
Y
E
C
G
K
A
F
V
Q
H
S
H
L
I
Q
Rat
Rattus norvegicus
NP_001025097
370
40876
S271
G
E
C
G
H
A
F
S
Q
S
S
N
L
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.9
30.1
30.7
N.A.
35.8
70.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
41.3
36.4
40.6
N.A.
44.8
78.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
33.3
100
N.A.
53.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
66.6
100
N.A.
80
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
84
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
17
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
17
0
0
0
0
17
0
17
0
0
17
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% I
% Lys:
0
0
0
0
50
0
0
17
0
0
0
0
0
0
17
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
17
100
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
0
0
0
0
17
0
17
0
67
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
0
0
34
0
0
0
67
0
0
0
0
0
17
% Q
% Arg:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
50
% R
% Ser:
0
17
0
0
0
17
0
50
0
67
100
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
17
0
0
0
0
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _