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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PYY All Species: 14.55
Human Site: S89 Identified Species: 35.56
UniProt: P10082 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10082 NP_004151.2 97 11046 S89 G E D R P V R S R S E G P D L
Chimpanzee Pan troglodytes XP_523780 101 11372 S89 G E D R P F A S A G R R A Q T
Rhesus Macaque Macaca mulatta Q9XSW6 97 10822 T89 S T E N V P R T R L E D P S M
Dog Lupus familis XP_848846 97 10909 S89 G E D R R A K S W P G G E Y M
Cat Felis silvestris
Mouse Mus musculus Q9EPS2 98 11045 P89 D S D S E N L P F R P E G L D
Rat Rattus norvegicus P10631 98 11102 R89 D S E N L P F R S R P E G V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512214 97 11071 T89 S T E N I P R T R F E D P S M
Chicken Gallus gallus P28673 97 11078 S89 S T E N I P R S R F E D P S M
Frog Xenopus laevis P33689 97 11360 S89 N T E N I P R S R F E D P P M
Zebra Danio Brachydanio rerio Q9I8P2 97 11156 S89 D T E H K Q R S R Y D D S F M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.1 51.5 77.3 N.A. 71.4 73.4 N.A. 50.5 50.5 47.4 49.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 87.1 70 83.5 N.A. 74.4 78.5 N.A. 69 69 70 70 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 40 26.6 40 N.A. 6.6 0 N.A. 26.6 33.3 33.3 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 46.6 53.3 N.A. 6.6 6.6 N.A. 46.6 46.6 46.6 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 10 0 10 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 30 0 40 0 0 0 0 0 0 0 10 50 0 10 20 % D
% Glu: 0 30 60 0 10 0 0 0 0 0 50 20 10 0 0 % E
% Phe: 0 0 0 0 0 10 10 0 10 30 0 0 0 10 0 % F
% Gly: 30 0 0 0 0 0 0 0 0 10 10 20 20 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 30 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 10 0 0 10 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60 % M
% Asn: 10 0 0 50 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 20 50 0 10 0 10 20 0 50 10 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 30 10 0 60 10 60 20 10 10 0 0 0 % R
% Ser: 30 20 0 10 0 0 0 60 10 10 0 0 10 30 0 % S
% Thr: 0 50 0 0 0 0 0 20 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 10 10 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _