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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDX1
All Species:
23.33
Human Site:
T145
Identified Species:
42.78
UniProt:
P10109
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10109
NP_004100.1
184
19393
T145
L
D
L
A
Y
G
L
T
D
R
S
R
L
G
C
Chimpanzee
Pan troglodytes
XP_508877
253
26800
T214
L
D
L
A
Y
G
L
T
D
R
S
R
L
G
C
Rhesus Macaque
Macaca mulatta
XP_001105034
184
19299
T145
L
D
L
A
Y
G
L
T
D
R
S
R
L
G
C
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P46656
188
20104
T149
L
D
L
A
F
G
L
T
D
R
S
R
L
G
C
Rat
Rattus norvegicus
P24483
188
20116
T149
L
D
L
A
F
G
L
T
N
R
S
R
L
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508845
318
35033
T279
L
D
L
A
Y
G
L
T
D
T
S
R
L
G
C
Chicken
Gallus gallus
P13216
143
15464
E105
D
L
A
Y
G
L
T
E
T
S
R
L
G
C
Q
Frog
Xenopus laevis
Q5FWQ0
193
21343
Q154
L
D
M
A
P
L
L
Q
E
N
S
R
L
G
C
Zebra Danio
Brachydanio rerio
Q08C57
195
21450
Q156
L
D
M
A
P
L
L
Q
E
N
S
R
L
G
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P37193
172
19715
R133
L
D
M
A
P
F
L
R
E
N
S
R
L
G
C
Honey Bee
Apis mellifera
XP_397185
133
14636
L95
T
D
E
E
L
D
M
L
D
L
A
Y
E
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783792
131
14654
D93
D
E
E
E
D
M
L
D
L
A
Y
G
L
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12184
172
18914
Y134
N
D
M
L
D
L
A
Y
G
L
T
E
T
S
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.2
96.1
N.A.
N.A.
75
75.5
N.A.
44.3
66.8
34.7
31.2
N.A.
28.2
41.2
N.A.
48.3
Protein Similarity:
100
62.8
97.2
N.A.
N.A.
80.8
81.9
N.A.
50
71.1
52.3
49.2
N.A.
50
54.8
N.A.
58.7
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
86.6
N.A.
93.3
0
60
60
N.A.
60
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
93.3
0
73.3
73.3
N.A.
73.3
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
70
0
0
8
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
70
% C
% Asp:
16
85
0
0
16
8
0
8
47
0
0
0
0
0
8
% D
% Glu:
0
8
16
16
0
0
0
8
24
0
0
8
8
8
0
% E
% Phe:
0
0
0
0
16
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
47
0
0
8
0
0
8
8
70
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
70
8
47
8
8
31
77
8
8
16
0
8
77
8
0
% L
% Met:
0
0
31
0
0
8
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
24
0
0
0
0
0
% N
% Pro:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
8
0
39
8
70
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
0
0
8
70
0
0
8
0
% S
% Thr:
8
0
0
0
0
0
8
47
8
8
8
0
8
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
31
0
0
8
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _