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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDX1
All Species:
21.21
Human Site:
T78
Identified Species:
38.89
UniProt:
P10109
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10109
NP_004100.1
184
19393
T78
F
I
N
R
D
G
E
T
L
T
T
K
G
K
V
Chimpanzee
Pan troglodytes
XP_508877
253
26800
T147
F
I
N
R
D
G
E
T
L
T
T
K
G
K
V
Rhesus Macaque
Macaca mulatta
XP_001105034
184
19299
T78
F
I
N
R
D
G
E
T
L
T
T
K
G
K
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P46656
188
20104
T82
F
K
N
R
D
G
E
T
L
T
T
K
G
K
I
Rat
Rattus norvegicus
P24483
188
20116
T82
F
K
N
R
D
G
E
T
L
T
T
K
G
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508845
318
35033
K212
F
I
N
R
D
G
D
K
L
T
T
K
G
E
V
Chicken
Gallus gallus
P13216
143
15464
P44
K
L
T
A
K
G
K
P
G
D
S
L
L
D
V
Frog
Xenopus laevis
Q5FWQ0
193
21343
R89
F
L
D
R
S
G
Q
R
I
P
V
K
G
K
V
Zebra Danio
Brachydanio rerio
Q08C57
195
21450
R91
Y
I
D
R
S
G
R
R
I
P
V
Q
A
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P37193
172
19715
V71
K
D
G
K
R
T
K
V
Q
G
K
V
G
D
N
Honey Bee
Apis mellifera
XP_397185
133
14636
R34
F
V
K
A
S
G
E
R
I
K
A
K
G
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783792
131
14654
T32
F
L
N
R
D
G
E
T
F
T
V
K
A
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12184
172
18914
Q72
F
I
L
K
D
G
S
Q
K
T
Y
E
V
C
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.2
96.1
N.A.
N.A.
75
75.5
N.A.
44.3
66.8
34.7
31.2
N.A.
28.2
41.2
N.A.
48.3
Protein Similarity:
100
62.8
97.2
N.A.
N.A.
80.8
81.9
N.A.
50
71.1
52.3
49.2
N.A.
50
54.8
N.A.
58.7
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
93.3
N.A.
80
13.3
46.6
26.6
N.A.
6.6
40
N.A.
73.3
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
93.3
33.3
73.3
60
N.A.
20
60
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
0
0
0
0
8
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
16
0
62
0
8
0
0
8
0
0
0
16
0
% D
% Glu:
0
0
0
0
0
0
54
0
0
0
0
8
0
8
8
% E
% Phe:
77
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
93
0
0
8
8
0
0
70
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
47
0
0
0
0
0
0
24
0
0
0
0
0
16
% I
% Lys:
16
16
8
16
8
0
16
8
8
8
8
70
0
62
0
% K
% Leu:
0
24
8
0
0
0
0
0
47
0
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
54
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
8
0
16
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
8
8
0
0
8
0
0
0
% Q
% Arg:
0
0
0
70
8
0
8
24
0
0
0
0
0
8
0
% R
% Ser:
0
0
0
0
24
0
8
0
0
0
8
0
0
0
0
% S
% Thr:
0
0
8
0
0
8
0
47
0
62
47
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
8
0
0
24
8
8
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _