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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAP2A All Species: 21.21
Human Site: S122 Identified Species: 33.33
UniProt: P10114 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10114 NP_066361.1 183 20615 S122 G N K V D L E S E R E V S S S
Chimpanzee Pan troglodytes XP_001140638 589 63249 G528 G N K V D L E G E R E V S Y G
Rhesus Macaque Macaca mulatta XP_001088490 184 20704 S123 G N K V D L E S E R E V S S N
Dog Lupus familis XP_534168 335 38190 S274 G N K V D L E S E R E V S S N
Cat Felis silvestris
Mouse Mus musculus Q8BU31 183 20726 P122 G N K V D L E P E R E V M S S
Rat Rattus norvegicus P61227 183 20486 G122 G N K V D L E G E R E V S Y G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514804 244 27079 S122 G N K V D L E S E R E V L S A
Chicken Gallus gallus XP_001233104 403 43650 S342 G N K V D L E S E R E V S S N
Frog Xenopus laevis Q7ZXH7 184 20815 D122 G N K C D L E D E R V V G K E
Zebra Danio Brachydanio rerio Q6TEN1 184 20809 D122 G N K C D L E D E R V V G K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08645 184 20845 E122 G N K C D L E E E R V V G K E
Honey Bee Apis mellifera XP_001120003 181 20317 H122 A N K L D L E H Q R E V D T A
Nematode Worm Caenorhab. elegans NP_506707 181 20375 H122 G N K C D L S H Q R Q V R S E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P13856 272 30372 N122 G N K A D L I N E R V I S V E
Red Bread Mold Neurospora crassa Q01387 229 25331 T146 G N K S D R V T E R E V S T Q
Conservation
Percent
Protein Identity: 100 28.1 97.8 52.5 N.A. 91.2 90.7 N.A. 70.4 44.6 61.4 60.3 N.A. 59.7 71.5 68.3 N.A.
Protein Similarity: 100 29.3 98.9 54.6 N.A. 96.1 94.5 N.A. 73.3 45.4 76.6 75 N.A. 76 85.7 80.3 N.A.
P-Site Identity: 100 80 93.3 93.3 N.A. 86.6 80 N.A. 86.6 93.3 60 60 N.A. 60 53.3 53.3 N.A.
P-Site Similarity: 100 80 100 100 N.A. 86.6 80 N.A. 93.3 100 60 60 N.A. 60 80 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 37.1 41
Protein Similarity: N.A. N.A. N.A. N.A. 52.2 57.6
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 60
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 14 % A
% Cys: 0 0 0 27 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 100 0 0 14 0 0 0 0 7 0 0 % D
% Glu: 0 0 0 0 0 0 80 7 87 0 67 0 0 0 34 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 94 0 0 0 0 0 0 14 0 0 0 0 20 0 14 % G
% His: 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % I
% Lys: 0 0 100 0 0 0 0 0 0 0 0 0 0 20 0 % K
% Leu: 0 0 0 7 0 94 0 0 0 0 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 100 0 0 0 0 0 7 0 0 0 0 0 0 20 % N
% Pro: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 14 0 7 0 0 0 7 % Q
% Arg: 0 0 0 0 0 7 0 0 0 100 0 0 7 0 0 % R
% Ser: 0 0 0 7 0 0 7 34 0 0 0 0 54 47 14 % S
% Thr: 0 0 0 0 0 0 0 7 0 0 0 0 0 14 0 % T
% Val: 0 0 0 54 0 0 7 0 0 0 27 94 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _