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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAP2A All Species: 46.06
Human Site: S146 Identified Species: 72.38
UniProt: P10114 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10114 NP_066361.1 183 20615 S146 G C P F M E T S A K S K T M V
Chimpanzee Pan troglodytes XP_001140638 589 63249 S552 S C P F M E T S A K N K A S V
Rhesus Macaque Macaca mulatta XP_001088490 184 20704 S147 G C P F M E T S A K S K T M V
Dog Lupus familis XP_534168 335 38190 S298 G C P F M E T S A K S K T M V
Cat Felis silvestris
Mouse Mus musculus Q8BU31 183 20726 S146 G C P F M E T S A K S K S M V
Rat Rattus norvegicus P61227 183 20486 S146 S C P F M E T S A K N K A S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514804 244 27079 S146 G C P F M E T S A K S K T M V
Chicken Gallus gallus XP_001233104 403 43650 S366 G C P F M E T S A K S K T M V
Frog Xenopus laevis Q7ZXH7 184 20815 S147 N C A F L E S S A K S K I N V
Zebra Danio Brachydanio rerio Q6TEN1 184 20809 S147 S C A F L E S S A K S K I N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08645 184 20845 S146 N C A F M E T S A K A K V N V
Honey Bee Apis mellifera XP_001120003 181 20317 A145 W G C P F V E A S A K H R T N
Nematode Worm Caenorhab. elegans NP_506707 181 20375 C145 W S C P F T E C S A K N N Q N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P13856 272 30372 S147 R V P F Y E T S A L L R S N V
Red Bread Mold Neurospora crassa Q01387 229 25331 S170 G C E F T E A S A K T R T N V
Conservation
Percent
Protein Identity: 100 28.1 97.8 52.5 N.A. 91.2 90.7 N.A. 70.4 44.6 61.4 60.3 N.A. 59.7 71.5 68.3 N.A.
Protein Similarity: 100 29.3 98.9 54.6 N.A. 96.1 94.5 N.A. 73.3 45.4 76.6 75 N.A. 76 85.7 80.3 N.A.
P-Site Identity: 100 73.3 100 100 N.A. 93.3 73.3 N.A. 100 100 60 60 N.A. 66.6 0 0 N.A.
P-Site Similarity: 100 80 100 100 N.A. 100 80 N.A. 100 100 73.3 73.3 N.A. 73.3 13.3 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 37.1 41
Protein Similarity: N.A. N.A. N.A. N.A. 52.2 57.6
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 60
P-Site Similarity: N.A. N.A. N.A. N.A. 60 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 0 0 7 7 87 14 7 0 14 0 0 % A
% Cys: 0 80 14 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 0 0 87 14 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 87 14 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 47 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 80 14 74 0 0 0 % K
% Leu: 0 0 0 0 14 0 0 0 0 7 7 0 0 0 0 % L
% Met: 0 0 0 0 60 0 0 0 0 0 0 0 0 40 0 % M
% Asn: 14 0 0 0 0 0 0 0 0 0 14 7 7 34 14 % N
% Pro: 0 0 60 14 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 7 0 0 0 0 0 0 0 0 0 0 14 7 0 0 % R
% Ser: 20 7 0 0 0 0 14 87 14 0 54 0 14 14 0 % S
% Thr: 0 0 0 0 7 7 67 0 0 0 7 0 40 7 0 % T
% Val: 0 7 0 0 0 7 0 0 0 0 0 0 7 0 87 % V
% Trp: 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _