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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TROVE2 All Species: 36.36
Human Site: S186 Identified Species: 72.73
UniProt: P10155 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10155 NP_001035828.1 538 60671 S186 H K D L L R L S H L K P S S E
Chimpanzee Pan troglodytes XP_001166825 538 60638 S186 H K D L L R L S H L K P S S E
Rhesus Macaque Macaca mulatta XP_001105371 205 23292
Dog Lupus familis XP_536115 538 60529 S186 H K D L L R L S H L K P S S E
Cat Felis silvestris
Mouse Mus musculus O08848 538 60105 S186 H K D L L R L S H L K P S S E
Rat Rattus norvegicus NP_001100653 538 60024 S186 H K D L L R L S H L K P N S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516992 539 60168 S187 H R D L L R L S H L K P A S E
Chicken Gallus gallus XP_422201 538 60344 S186 H K D L L R L S H L K P A S E
Frog Xenopus laevis P42700 538 60670 S186 H K D L L R L S H I K P A N E
Zebra Danio Brachydanio rerio NP_001032474 534 58757 S182 H Q D L L R L S H M K P A N D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27274 643 72824 A258 H R D L F R L A H P N L M D S
Sea Urchin Strong. purpuratus XP_791301 526 58055 A170 H R D L I R L A H V K P P A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 37.7 97.4 N.A. 89.7 89.5 N.A. 86.4 80.8 78.4 52.9 N.A. N.A. N.A. 35.9 36.8
Protein Similarity: 100 100 37.9 99 N.A. 95.3 95.3 N.A. 93.8 90.7 89.5 71.5 N.A. N.A. N.A. 52.7 58.3
P-Site Identity: 100 100 0 100 N.A. 100 93.3 N.A. 86.6 93.3 80 66.6 N.A. N.A. N.A. 40 60
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 100 100 100 100 N.A. N.A. N.A. 53.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 17 0 0 0 0 34 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 92 0 0 0 0 0 0 0 0 0 0 9 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 92 0 0 0 0 0 0 0 92 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 0 59 0 0 0 0 0 0 0 0 84 0 0 0 0 % K
% Leu: 0 0 0 92 75 0 92 0 0 59 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 0 9 17 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 0 84 9 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 25 0 0 0 92 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 75 0 0 0 0 34 59 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _