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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TROVE2
All Species:
34.24
Human Site:
T425
Identified Species:
68.48
UniProt:
P10155
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10155
NP_001035828.1
538
60671
T425
E
M
V
P
C
P
V
T
T
D
M
T
L
Q
Q
Chimpanzee
Pan troglodytes
XP_001166825
538
60638
T425
E
M
V
P
C
P
V
T
T
D
M
T
L
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001105371
205
23292
L96
Q
E
P
M
L
F
A
L
A
I
C
S
Q
C
S
Dog
Lupus familis
XP_536115
538
60529
T425
E
M
V
P
C
P
V
T
T
D
M
T
L
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
O08848
538
60105
T425
D
M
V
P
F
P
V
T
T
D
M
T
L
Q
Q
Rat
Rattus norvegicus
NP_001100653
538
60024
T425
D
M
V
P
F
P
V
T
T
D
M
T
L
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516992
539
60168
T426
E
M
V
P
C
P
V
T
A
D
M
T
L
R
Q
Chicken
Gallus gallus
XP_422201
538
60344
T425
E
L
V
P
C
P
V
T
A
D
M
T
L
P
Q
Frog
Xenopus laevis
P42700
538
60670
T425
E
M
L
P
C
P
I
T
V
N
M
L
L
H
E
Zebra Danio
Brachydanio rerio
NP_001032474
534
58757
V421
G
N
L
L
P
C
T
V
S
S
D
M
T
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27274
643
72824
T529
K
L
T
E
L
P
F
T
K
D
W
K
I
G
Q
Sea Urchin
Strong. purpuratus
XP_791301
526
58055
T413
E
L
K
E
I
P
I
T
A
N
M
K
L
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
37.7
97.4
N.A.
89.7
89.5
N.A.
86.4
80.8
78.4
52.9
N.A.
N.A.
N.A.
35.9
36.8
Protein Similarity:
100
100
37.9
99
N.A.
95.3
95.3
N.A.
93.8
90.7
89.5
71.5
N.A.
N.A.
N.A.
52.7
58.3
P-Site Identity:
100
100
0
100
N.A.
86.6
86.6
N.A.
86.6
80
53.3
0
N.A.
N.A.
N.A.
26.6
33.3
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
93.3
86.6
80
13.3
N.A.
N.A.
N.A.
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
34
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
50
9
0
0
0
0
9
0
0
9
0
% C
% Asp:
17
0
0
0
0
0
0
0
0
67
9
0
0
0
9
% D
% Glu:
59
9
0
17
0
0
0
0
0
0
0
0
0
9
9
% E
% Phe:
0
0
0
0
17
9
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
9
0
17
0
0
9
0
0
9
0
0
% I
% Lys:
9
0
9
0
0
0
0
0
9
0
0
17
0
0
0
% K
% Leu:
0
25
17
9
17
0
0
9
0
0
0
9
75
9
0
% L
% Met:
0
59
0
9
0
0
0
0
0
0
75
9
0
0
9
% M
% Asn:
0
9
0
0
0
0
0
0
0
17
0
0
0
0
0
% N
% Pro:
0
0
9
67
9
84
0
0
0
0
0
0
0
9
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
9
42
67
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
0
0
0
0
0
0
0
0
9
9
0
9
0
0
9
% S
% Thr:
0
0
9
0
0
0
9
84
42
0
0
59
9
0
0
% T
% Val:
0
0
59
0
0
0
59
9
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _