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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TROVE2
All Species:
34.85
Human Site:
Y228
Identified Species:
69.7
UniProt:
P10155
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10155
NP_001035828.1
538
60671
Y228
E
T
E
K
L
L
K
Y
L
E
A
V
E
K
V
Chimpanzee
Pan troglodytes
XP_001166825
538
60638
Y228
E
T
E
K
L
L
K
Y
L
E
A
V
E
K
V
Rhesus Macaque
Macaca mulatta
XP_001105371
205
23292
Dog
Lupus familis
XP_536115
538
60529
Y228
E
T
E
K
L
L
K
Y
L
E
A
V
E
K
V
Cat
Felis silvestris
Mouse
Mus musculus
O08848
538
60105
Y228
E
A
E
K
L
L
K
Y
L
E
A
V
E
K
V
Rat
Rattus norvegicus
NP_001100653
538
60024
Y228
E
T
D
K
L
L
K
Y
L
E
A
V
E
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516992
539
60168
Y229
E
T
E
K
L
F
Q
Y
L
E
A
V
E
R
V
Chicken
Gallus gallus
XP_422201
538
60344
Y228
E
T
E
K
L
L
K
Y
L
E
A
V
D
R
V
Frog
Xenopus laevis
P42700
538
60670
Y228
E
T
E
K
V
L
K
Y
L
E
A
T
E
R
V
Zebra Danio
Brachydanio rerio
NP_001032474
534
58757
Y224
D
L
Q
K
V
F
A
Y
L
E
A
V
E
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27274
643
72824
E300
K
R
K
M
S
V
E
E
V
A
E
V
E
K
V
Sea Urchin
Strong. purpuratus
XP_791301
526
58055
T212
D
D
S
T
R
A
L
T
E
F
L
R
D
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
37.7
97.4
N.A.
89.7
89.5
N.A.
86.4
80.8
78.4
52.9
N.A.
N.A.
N.A.
35.9
36.8
Protein Similarity:
100
100
37.9
99
N.A.
95.3
95.3
N.A.
93.8
90.7
89.5
71.5
N.A.
N.A.
N.A.
52.7
58.3
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
80
86.6
80
53.3
N.A.
N.A.
N.A.
26.6
0
P-Site Similarity:
100
100
0
100
N.A.
93.3
100
N.A.
93.3
100
93.3
73.3
N.A.
N.A.
N.A.
60
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
9
0
0
9
75
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
9
0
0
0
0
0
0
0
0
0
17
0
9
% D
% Glu:
67
0
59
0
0
0
9
9
9
75
9
0
75
0
0
% E
% Phe:
0
0
0
0
0
17
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
9
75
0
0
59
0
0
0
0
0
0
59
0
% K
% Leu:
0
9
0
0
59
59
9
0
75
0
9
0
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
9
0
0
0
0
0
0
9
0
25
0
% R
% Ser:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
59
0
9
0
0
0
9
0
0
0
9
0
0
0
% T
% Val:
0
0
0
0
17
9
0
0
9
0
0
75
0
9
75
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _