KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYBL1
All Species:
26.36
Human Site:
S458
Identified Species:
48.33
UniProt:
P10243
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10243
NP_001073885.1
752
85887
S458
R
K
M
R
V
G
H
S
P
G
S
E
L
R
D
Chimpanzee
Pan troglodytes
XP_001158417
885
100326
S471
R
K
M
R
V
G
H
S
P
G
S
E
L
R
D
Rhesus Macaque
Macaca mulatta
XP_001095486
752
85763
S458
R
K
M
R
V
G
L
S
P
G
S
E
L
R
D
Dog
Lupus familis
XP_544108
751
85690
S458
R
R
M
R
V
G
Q
S
P
G
S
E
H
S
D
Cat
Felis silvestris
Mouse
Mus musculus
P51960
751
85709
S457
K
R
I
R
V
G
Q
S
A
G
S
E
L
G
S
Rat
Rattus norvegicus
NP_001100102
749
85205
S455
K
R
L
R
V
G
Q
S
A
G
S
E
L
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511778
753
85883
S459
R
R
I
R
V
G
H
S
P
V
S
D
H
N
D
Chicken
Gallus gallus
P52550
757
85990
S463
K
R
L
R
A
G
Q
S
P
V
N
E
L
N
D
Frog
Xenopus laevis
Q05935
728
83558
K439
P
T
I
L
R
K
K
K
I
H
P
D
L
S
L
Zebra Danio
Brachydanio rerio
XP_686862
739
83647
D445
K
K
R
R
E
G
G
D
Q
S
P
A
E
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797351
686
76826
L406
D
T
S
L
S
S
T
L
N
T
P
N
T
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P20024
340
36221
I60
K
S
C
R
L
R
W
I
N
Y
L
R
P
D
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7G7
776
86488
H448
K
V
P
A
L
P
W
H
P
S
S
S
E
G
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.4
98.8
94
N.A.
91.6
92.1
N.A.
86.8
79.1
59.9
55.4
N.A.
N.A.
N.A.
N.A.
36
Protein Similarity:
100
84.4
99
96.8
N.A.
95.7
96.4
N.A.
92
86.7
73.9
69.6
N.A.
N.A.
N.A.
N.A.
53
P-Site Identity:
100
100
93.3
73.3
N.A.
53.3
53.3
N.A.
60
46.6
6.6
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
80
N.A.
73.3
80
N.A.
80
73.3
20
26.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
20.8
N.A.
22.4
N.A.
N.A.
Protein Similarity:
N.A.
30.1
N.A.
41.7
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
16
0
0
8
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
0
0
0
16
0
8
47
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
54
16
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
70
8
0
0
47
0
0
0
24
0
% G
% His:
0
0
0
0
0
0
24
8
0
8
0
0
16
0
0
% H
% Ile:
0
0
24
0
0
0
0
8
8
0
0
0
0
0
0
% I
% Lys:
47
31
0
0
0
8
8
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
16
16
16
0
8
8
0
0
8
0
54
0
24
% L
% Met:
0
0
31
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
16
0
8
8
0
16
0
% N
% Pro:
8
0
8
0
0
8
0
0
54
0
24
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
31
0
8
0
0
0
0
0
0
% Q
% Arg:
39
39
8
77
8
8
0
0
0
0
0
8
0
24
16
% R
% Ser:
0
8
8
0
8
8
0
62
0
16
62
8
0
24
8
% S
% Thr:
0
16
0
0
0
0
8
0
0
8
0
0
8
0
0
% T
% Val:
0
8
0
0
54
0
0
0
0
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _