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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBL2 All Species: 12.42
Human Site: S350 Identified Species: 21.03
UniProt: P10244 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10244 NP_002457.1 700 78764 S350 S L V Q L Q A S H Q Q Q V L P
Chimpanzee Pan troglodytes XP_514658 769 86303 S350 S L V Q L Q A S H Q Q Q V L P
Rhesus Macaque Macaca mulatta XP_001084853 700 78675 S350 S L V Q L Q A S Q Q Q Q V L P
Dog Lupus familis XP_534424 883 97262 S533 S P V Q P S P S Q Q Q Q T L P
Cat Felis silvestris
Mouse Mus musculus P48972 704 79084 Q353 Q P Q T S Q Q Q Q E E A L Q S
Rat Rattus norvegicus NP_001100006 704 79549 Q354 L Q T P Q Q Q Q Q H Q Q A L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511778 753 85883 A386 F D L S D A A A A S P A K P T
Chicken Gallus gallus Q03237 686 77718 S333 P S A G S S S S S N S P V R Q
Frog Xenopus laevis P52551 743 82891 I353 N K G E L I P I S P Q P Q T A
Zebra Danio Brachydanio rerio NP_001003867 633 70853 P307 T M S D F D L P E E S Q S S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797351 686 76826 E356 A L L D L S R E A S G G L I P
Poplar Tree Populus trichocarpa
Maize Zea mays P20024 340 36221 L14 P C C A K V G L N R G S W T P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7G7 776 86488 N422 R N M V D P Q N G K G S L C S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O13493 324 36522
Conservation
Percent
Protein Identity: 100 88 98.2 72.5 N.A. 85.2 87.7 N.A. 38.3 72.5 54.2 52.1 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 89.7 98.7 74.7 N.A. 89.4 91.3 N.A. 54.5 81.5 69 65.8 N.A. N.A. N.A. N.A. 54
P-Site Identity: 100 100 93.3 60 N.A. 6.6 26.6 N.A. 6.6 13.3 13.3 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 93.3 60 N.A. 26.6 26.6 N.A. 20 20 26.6 26.6 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. 20.1 N.A. 25.5 N.A. 20.7
Protein Similarity: N.A. 31.8 N.A. 40.8 N.A. 29.5
P-Site Identity: N.A. 6.6 N.A. 0 N.A. 0
P-Site Similarity: N.A. 20 N.A. 26.6 N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 0 8 29 8 15 0 0 15 8 0 8 % A
% Cys: 0 8 8 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 8 0 15 15 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 8 8 15 8 0 0 0 8 % E
% Phe: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 8 0 0 8 0 8 0 22 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 15 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 8 0 0 0 0 0 8 0 % I
% Lys: 0 8 0 0 8 0 0 0 0 8 0 0 8 0 0 % K
% Leu: 8 29 15 0 36 0 8 8 0 0 0 0 22 36 0 % L
% Met: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 0 0 8 8 8 0 0 0 0 0 % N
% Pro: 15 15 0 8 8 8 15 8 0 8 8 15 0 8 43 % P
% Gln: 8 8 8 29 8 36 22 15 29 29 43 43 8 8 8 % Q
% Arg: 8 0 0 0 0 0 8 0 0 8 0 0 0 8 0 % R
% Ser: 29 8 8 8 15 22 8 36 15 15 15 15 8 8 22 % S
% Thr: 8 0 8 8 0 0 0 0 0 0 0 0 8 15 8 % T
% Val: 0 0 29 8 0 8 0 0 0 0 0 0 29 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _