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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBL2 All Species: 24.24
Human Site: S408 Identified Species: 41.03
UniProt: P10244 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10244 NP_002457.1 700 78764 S408 S G I G T P P S V L K R Q R K
Chimpanzee Pan troglodytes XP_514658 769 86303 S408 S G I G T P P S V L K R Q R K
Rhesus Macaque Macaca mulatta XP_001084853 700 78675 S408 S G I G T P P S V L K R Q R K
Dog Lupus familis XP_534424 883 97262 S591 L G I G T P P S V L K R Q K K
Cat Felis silvestris
Mouse Mus musculus P48972 704 79084 S411 S G I G T P P S V L K R Q K K
Rat Rattus norvegicus NP_001100006 704 79549 S412 S G I G T P P S V L K R Q K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511778 753 85883 P444 N E V K F S T P P T I L R K K
Chicken Gallus gallus Q03237 686 77718 L391 F G T P P S V L K R Q K K R K
Frog Xenopus laevis P52551 743 82891 S411 P V K S L P F S P S Q F L N F
Zebra Danio Brachydanio rerio NP_001003867 633 70853 N365 I A L S P D P N D S M T P K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797351 686 76826 Y414 N T P N T S R Y K T P Q G T P
Poplar Tree Populus trichocarpa
Maize Zea mays P20024 340 36221 F72 P D L K R G N F T D E E E E A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7G7 776 86488 A480 L P R N D S N A P I Q G C R L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O13493 324 36522 K56 E R W H Q N L K P G L N H G P
Conservation
Percent
Protein Identity: 100 88 98.2 72.5 N.A. 85.2 87.7 N.A. 38.3 72.5 54.2 52.1 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 89.7 98.7 74.7 N.A. 89.4 91.3 N.A. 54.5 81.5 69 65.8 N.A. N.A. N.A. N.A. 54
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 6.6 20 13.3 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 33.3 40 20 26.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. 20.1 N.A. 25.5 N.A. 20.7
Protein Similarity: N.A. 31.8 N.A. 40.8 N.A. 29.5
P-Site Identity: N.A. 0 N.A. 6.6 N.A. 0
P-Site Similarity: N.A. 20 N.A. 26.6 N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 8 0 0 8 8 0 0 8 8 0 0 0 0 0 % D
% Glu: 8 8 0 0 0 0 0 0 0 0 8 8 8 8 0 % E
% Phe: 8 0 0 0 8 0 8 8 0 0 0 8 0 0 8 % F
% Gly: 0 50 0 43 0 8 0 0 0 8 0 8 8 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 0 43 0 0 0 0 0 0 8 8 0 0 0 0 % I
% Lys: 0 0 8 15 0 0 0 8 15 0 43 8 8 36 58 % K
% Leu: 15 0 15 0 8 0 8 8 0 43 8 8 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 15 0 0 15 0 8 15 8 0 0 0 8 0 8 0 % N
% Pro: 15 8 8 8 15 50 50 8 29 0 8 0 8 0 15 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 22 8 43 0 0 % Q
% Arg: 0 8 8 0 8 0 8 0 0 8 0 43 8 36 0 % R
% Ser: 36 0 0 15 0 29 0 50 0 15 0 0 0 0 8 % S
% Thr: 0 8 8 0 50 0 8 0 8 15 0 8 0 8 0 % T
% Val: 0 8 8 0 0 0 8 0 43 0 0 0 0 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _