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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBL2 All Species: 13.03
Human Site: S622 Identified Species: 22.05
UniProt: P10244 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10244 NP_002457.1 700 78764 S622 N S S S L T L S G I K E D N S
Chimpanzee Pan troglodytes XP_514658 769 86303 S622 N P S S L T L S G I K R R Q Q
Rhesus Macaque Macaca mulatta XP_001084853 700 78675 S622 N S S S L T L S G I K E D N S
Dog Lupus familis XP_534424 883 97262 S805 S S S S L M V S G I K E D T S
Cat Felis silvestris
Mouse Mus musculus P48972 704 79084 P626 S S C G F T S P G S K E G N S
Rat Rattus norvegicus NP_001100006 704 79549 P626 S S S G F I L P G I K E D N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511778 753 85883 P664 T T S L L M I P L L E I H D N
Chicken Gallus gallus Q03237 686 77718 N605 N F L S R S L N L S S S N R K
Frog Xenopus laevis P52551 743 82891 L650 G T F T N T D L C P Q S L M D
Zebra Danio Brachydanio rerio NP_001003867 633 70853 L568 V L D Q G F I L G P N E S G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797351 686 76826 N617 K A L N E A F N M P S T P S P
Poplar Tree Populus trichocarpa
Maize Zea mays P20024 340 36221 N275 A N D W W L E N L E K E L G L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7G7 776 86488 T694 D E G D D C M T S R P S E S P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O13493 324 36522 D259 I G D L D E F D R R Q L A A F
Conservation
Percent
Protein Identity: 100 88 98.2 72.5 N.A. 85.2 87.7 N.A. 38.3 72.5 54.2 52.1 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 89.7 98.7 74.7 N.A. 89.4 91.3 N.A. 54.5 81.5 69 65.8 N.A. N.A. N.A. N.A. 54
P-Site Identity: 100 66.6 100 73.3 N.A. 46.6 66.6 N.A. 13.3 20 6.6 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 66.6 100 86.6 N.A. 53.3 73.3 N.A. 53.3 40 26.6 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. 20.1 N.A. 25.5 N.A. 20.7
Protein Similarity: N.A. 31.8 N.A. 40.8 N.A. 29.5
P-Site Identity: N.A. 13.3 N.A. 0 N.A. 0
P-Site Similarity: N.A. 26.6 N.A. 33.3 N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 8 0 0 0 0 0 0 8 8 0 % A
% Cys: 0 0 8 0 0 8 0 0 8 0 0 0 0 0 0 % C
% Asp: 8 0 22 8 15 0 8 8 0 0 0 0 29 8 8 % D
% Glu: 0 8 0 0 8 8 8 0 0 8 8 50 8 0 0 % E
% Phe: 0 8 8 0 15 8 15 0 0 0 0 0 0 0 8 % F
% Gly: 8 8 8 15 8 0 0 0 50 0 0 0 8 15 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 0 0 0 0 8 15 0 0 36 0 8 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 50 0 0 0 8 % K
% Leu: 0 8 15 15 36 8 36 15 22 8 0 8 15 0 8 % L
% Met: 0 0 0 0 0 15 8 0 8 0 0 0 0 8 0 % M
% Asn: 29 8 0 8 8 0 0 22 0 0 8 0 8 29 8 % N
% Pro: 0 8 0 0 0 0 0 22 0 22 8 0 8 0 22 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 15 0 0 8 8 % Q
% Arg: 0 0 0 0 8 0 0 0 8 15 0 8 8 8 0 % R
% Ser: 22 36 43 36 0 8 8 29 8 15 15 22 8 15 36 % S
% Thr: 8 15 0 8 0 36 0 8 0 0 0 8 0 8 0 % T
% Val: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _