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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBL2 All Species: 13.64
Human Site: T218 Identified Species: 23.08
UniProt: P10244 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10244 NP_002457.1 700 78764 T218 G L Q S A Q P T E G Q G S L L
Chimpanzee Pan troglodytes XP_514658 769 86303 T218 G L Q S A Q P T E G Q G S L L
Rhesus Macaque Macaca mulatta XP_001084853 700 78675 T218 G L Q S A Q P T E G Q G S L L
Dog Lupus familis XP_534424 883 97262 V401 G C Q S A R P V E E Q G S L M
Cat Felis silvestris
Mouse Mus musculus P48972 704 79084 D218 H Q G V Q P V D G Q G S L V S
Rat Rattus norvegicus NP_001100006 704 79549 E218 Q Q N V Q P V E G P G S L V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511778 753 85883 N224 L D H L Q T Q N Q F Y I P V Q
Chicken Gallus gallus Q03237 686 77718 S196 F L N E T K E S Q P L Y L L V
Frog Xenopus laevis P52551 743 82891 S218 D Q N H V L L S E P V E R S A
Zebra Danio Brachydanio rerio NP_001003867 633 70853 W177 D N A V K N H W N S T I K R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797351 686 76826 Y225 C S S S S K I Y T P D S D F M
Poplar Tree Populus trichocarpa
Maize Zea mays P20024 340 36221
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7G7 776 86488 S222 S S S S W M H S N G D E G S S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O13493 324 36522
Conservation
Percent
Protein Identity: 100 88 98.2 72.5 N.A. 85.2 87.7 N.A. 38.3 72.5 54.2 52.1 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 89.7 98.7 74.7 N.A. 89.4 91.3 N.A. 54.5 81.5 69 65.8 N.A. N.A. N.A. N.A. 54
P-Site Identity: 100 100 100 66.6 N.A. 0 0 N.A. 0 13.3 6.6 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 80 N.A. 6.6 6.6 N.A. 13.3 40 13.3 0 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. 20.1 N.A. 25.5 N.A. 20.7
Protein Similarity: N.A. 31.8 N.A. 40.8 N.A. 29.5
P-Site Identity: N.A. 0 N.A. 13.3 N.A. 0
P-Site Similarity: N.A. 0 N.A. 20 N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 29 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 8 0 0 0 0 0 8 0 0 15 0 8 0 0 % D
% Glu: 0 0 0 8 0 0 8 8 36 8 0 15 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % F
% Gly: 29 0 8 0 0 0 0 0 15 29 15 29 8 0 0 % G
% His: 8 0 8 8 0 0 15 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 15 0 0 0 % I
% Lys: 0 0 0 0 8 15 0 0 0 0 0 0 8 0 8 % K
% Leu: 8 29 0 8 0 8 8 0 0 0 8 0 22 36 22 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 15 % M
% Asn: 0 8 22 0 0 8 0 8 15 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 15 29 0 0 29 0 0 8 0 0 % P
% Gln: 8 22 29 0 22 22 8 0 15 8 29 0 0 0 8 % Q
% Arg: 0 0 0 0 0 8 0 0 0 0 0 0 8 8 0 % R
% Ser: 8 15 15 43 8 0 0 22 0 8 0 22 29 15 22 % S
% Thr: 0 0 0 0 8 8 0 22 8 0 8 0 0 0 0 % T
% Val: 0 0 0 22 8 0 15 8 0 0 8 0 0 22 8 % V
% Trp: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _