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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBL2 All Species: 26.67
Human Site: T538 Identified Species: 45.13
UniProt: P10244 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10244 NP_002457.1 700 78764 T538 P L K P L P Q T P H L E E D L
Chimpanzee Pan troglodytes XP_514658 769 86303 T538 P L K P L P Q T P H L E E D L
Rhesus Macaque Macaca mulatta XP_001084853 700 78675 T538 P L K P L P Q T P H L E E D L
Dog Lupus familis XP_534424 883 97262 T721 P L K P L P Q T P H L E E D L
Cat Felis silvestris
Mouse Mus musculus P48972 704 79084 Q541 G P L K P L P Q T P H L E E D
Rat Rattus norvegicus NP_001100006 704 79549 T542 P L K P L P Q T P H L E E D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511778 753 85883 L574 Q E K K Y G P L K I V S Q P L
Chicken Gallus gallus Q03237 686 77718 T521 P I R P L P Q T P H L E E D L
Frog Xenopus laevis P52551 743 82891 S541 P M K K V R K S L A L D I I D
Zebra Danio Brachydanio rerio NP_001003867 633 70853 A495 I V E D E A P A E K K R K Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797351 686 76826 K544 L K R A I L Q K A E S I S P V
Poplar Tree Populus trichocarpa
Maize Zea mays P20024 340 36221 P202 A A Q P M P S P S S S S S L T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7G7 776 86488 S610 I R Q L M I S S M N C T T P L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O13493 324 36522 Q186 P S R P Q Q Q Q Q Q Q Q Q Q A
Conservation
Percent
Protein Identity: 100 88 98.2 72.5 N.A. 85.2 87.7 N.A. 38.3 72.5 54.2 52.1 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 89.7 98.7 74.7 N.A. 89.4 91.3 N.A. 54.5 81.5 69 65.8 N.A. N.A. N.A. N.A. 54
P-Site Identity: 100 100 100 100 N.A. 6.6 100 N.A. 13.3 86.6 20 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 13.3 100 N.A. 26.6 100 53.3 26.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. 20.1 N.A. 25.5 N.A. 20.7
Protein Similarity: N.A. 31.8 N.A. 40.8 N.A. 29.5
P-Site Identity: N.A. 13.3 N.A. 6.6 N.A. 20
P-Site Similarity: N.A. 26.6 N.A. 33.3 N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 0 8 0 8 8 8 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 8 0 43 15 % D
% Glu: 0 8 8 0 8 0 0 0 8 8 0 43 50 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 43 8 0 0 0 0 % H
% Ile: 15 8 0 0 8 8 0 0 0 8 0 8 8 8 0 % I
% Lys: 0 8 50 22 0 0 8 8 8 8 8 0 8 0 0 % K
% Leu: 8 36 8 8 43 15 0 8 8 0 50 8 0 8 58 % L
% Met: 0 8 0 0 15 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 58 8 0 58 8 50 22 8 43 8 0 0 0 22 0 % P
% Gln: 8 0 15 0 8 8 58 15 8 8 8 8 15 15 0 % Q
% Arg: 0 8 22 0 0 8 0 0 0 0 0 8 0 0 0 % R
% Ser: 0 8 0 0 0 0 15 15 8 8 15 15 15 0 0 % S
% Thr: 0 0 0 0 0 0 0 43 8 0 0 8 8 0 8 % T
% Val: 0 8 0 0 8 0 0 0 0 0 8 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _