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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBL2 All Species: 20.61
Human Site: T610 Identified Species: 34.87
UniProt: P10244 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10244 NP_002457.1 700 78764 T610 P K S L S L P T T A P S N S S
Chimpanzee Pan troglodytes XP_514658 769 86303 T610 P K S L S L P T T A P S N P S
Rhesus Macaque Macaca mulatta XP_001084853 700 78675 T610 P K S L S L P T T A P S N S S
Dog Lupus familis XP_534424 883 97262 T793 P K V L S L P T N V L S S S S
Cat Felis silvestris
Mouse Mus musculus P48972 704 79084 T614 P K P L S L P T S V T P S S C
Rat Rattus norvegicus NP_001100006 704 79549 T614 P K T L S L P T S V P S S S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511778 753 85883 S652 E D I S D L Q S E N I F T T S
Chicken Gallus gallus Q03237 686 77718 R593 P K T I C F K R T Q P V N F L
Frog Xenopus laevis P52551 743 82891 F638 N T E T A T P F K T E N G T F
Zebra Danio Brachydanio rerio NP_001003867 633 70853 V556 P P V S S C A V K E E N V L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797351 686 76826 G605 G Q G S I L G G E M S M K A L
Poplar Tree Populus trichocarpa
Maize Zea mays P20024 340 36221 A263 T A V S T S E A E E A A A N D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7G7 776 86488 L682 L A N D F S R L D V M L D E G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O13493 324 36522 P247 P F S T L P S P T T S S I G D
Conservation
Percent
Protein Identity: 100 88 98.2 72.5 N.A. 85.2 87.7 N.A. 38.3 72.5 54.2 52.1 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 89.7 98.7 74.7 N.A. 89.4 91.3 N.A. 54.5 81.5 69 65.8 N.A. N.A. N.A. N.A. 54
P-Site Identity: 100 93.3 100 66.6 N.A. 53.3 73.3 N.A. 13.3 33.3 6.6 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 93.3 100 73.3 N.A. 66.6 93.3 N.A. 26.6 46.6 26.6 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. 20.1 N.A. 25.5 N.A. 20.7
Protein Similarity: N.A. 31.8 N.A. 40.8 N.A. 29.5
P-Site Identity: N.A. 0 N.A. 0 N.A. 26.6
P-Site Similarity: N.A. 20 N.A. 13.3 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 8 0 8 8 0 22 8 8 8 8 0 % A
% Cys: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 8 0 8 8 0 0 0 8 0 0 0 8 0 22 % D
% Glu: 8 0 8 0 0 0 8 0 22 15 15 0 0 8 0 % E
% Phe: 0 8 0 0 8 8 0 8 0 0 0 8 0 8 8 % F
% Gly: 8 0 8 0 0 0 8 8 0 0 0 0 8 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 8 0 0 0 0 0 8 0 8 0 0 % I
% Lys: 0 50 0 0 0 0 8 0 15 0 0 0 8 0 0 % K
% Leu: 8 0 0 43 8 58 0 8 0 0 8 8 0 8 15 % L
% Met: 0 0 0 0 0 0 0 0 0 8 8 8 0 0 0 % M
% Asn: 8 0 8 0 0 0 0 0 8 8 0 15 29 8 0 % N
% Pro: 65 8 8 0 0 8 50 8 0 0 36 8 0 8 0 % P
% Gln: 0 8 0 0 0 0 8 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % R
% Ser: 0 0 29 29 50 15 8 8 15 0 15 43 22 36 43 % S
% Thr: 8 8 15 15 8 8 0 43 36 15 8 0 8 15 0 % T
% Val: 0 0 22 0 0 0 0 8 0 29 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _