Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAA All Species: 28.48
Human Site: S454 Identified Species: 56.97
UniProt: P10253 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10253 NP_000143.2 952 105319 S454 S S S G P A G S Y R P Y D E G
Chimpanzee Pan troglodytes XP_001160562 952 105395 S454 S S S G P A G S Y R P Y D E G
Rhesus Macaque Macaca mulatta XP_001109939 952 105411 S454 S I S G P A G S Y R P Y D E G
Dog Lupus familis XP_850649 951 105652 S454 S S S S P P G S Y R P Y D E G
Cat Felis silvestris
Mouse Mus musculus P70699 953 106229 S454 S S A G P A G S Y R P Y D E G
Rat Rattus norvegicus Q6P7A9 953 106188 S454 S S S G P A G S Y R P Y D E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232641 930 104640 S450 S S T S P H G S Y W P F D E G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921957 882 99143 G411 F D D G L K K G V F I N N S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392880 865 100033 A394 P D F T N P K A R N Y Y F R M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787183 1049 116156 S559 S S S Q S P G S Y A P Y D T G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 I425 V S W W G D E I K R F H D L V
Baker's Yeast Sacchar. cerevisiae P38138 954 110248 D470 I D P H L K K D Y E I S D R V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 95.4 83.9 N.A. 80 81.3 N.A. N.A. 50.4 N.A. 53.2 N.A. N.A. 37.7 N.A. 43
Protein Similarity: 100 98.9 97.6 89.5 N.A. 88.4 88.2 N.A. N.A. 66 N.A. 67.7 N.A. N.A. 53.1 N.A. 56.8
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 100 N.A. N.A. 66.6 N.A. 6.6 N.A. N.A. 6.6 N.A. 66.6
P-Site Similarity: 100 100 93.3 86.6 N.A. 100 100 N.A. N.A. 80 N.A. 13.3 N.A. N.A. 13.3 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. 32.7 23 N.A.
Protein Similarity: N.A. N.A. N.A. 50.5 43.7 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 42 0 9 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 25 9 0 0 9 0 9 0 0 0 0 84 0 0 % D
% Glu: 0 0 0 0 0 0 9 0 0 9 0 0 0 59 0 % E
% Phe: 9 0 9 0 0 0 0 0 0 9 9 9 9 0 0 % F
% Gly: 0 0 0 50 9 0 67 9 0 0 0 0 0 0 67 % G
% His: 0 0 0 9 0 9 0 0 0 0 0 9 0 0 0 % H
% Ile: 9 9 0 0 0 0 0 9 0 0 17 0 0 0 0 % I
% Lys: 0 0 0 0 0 17 25 0 9 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 17 0 0 0 0 0 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 9 0 0 0 0 9 0 9 9 0 0 % N
% Pro: 9 0 9 0 59 25 0 0 0 0 67 0 0 0 0 % P
% Gln: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 9 59 0 0 0 17 0 % R
% Ser: 67 67 50 17 9 0 0 67 0 0 0 9 0 9 0 % S
% Thr: 0 0 9 9 0 0 0 0 0 0 0 0 0 9 9 % T
% Val: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 17 % V
% Trp: 0 0 9 9 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 75 0 9 67 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _