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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAA All Species: 16.06
Human Site: S679 Identified Species: 32.12
UniProt: P10253 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10253 NP_000143.2 952 105319 S679 R N H N S L L S L P Q E P Y S
Chimpanzee Pan troglodytes XP_001160562 952 105395 N679 R N H N G L L N L P Q E P Y S
Rhesus Macaque Macaca mulatta XP_001109939 952 105411 N679 R N H N G L L N L P Q E P Y S
Dog Lupus familis XP_850649 951 105652 S679 R N H N D L N S L P Q E P Y R
Cat Felis silvestris
Mouse Mus musculus P70699 953 106229 S679 R N H N D L N S V P Q E P Y R
Rat Rattus norvegicus Q6P7A9 953 106188 S679 R N H N D L N S L P Q E P Y R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232641 930 104640 M658 E E L C T R W M Q L G A F Y P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921957 882 99143 G611 C V R W T Q L G A F Y P F M R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392880 865 100033 S594 G D L V I K S S K R A L T I R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787183 1049 116156 Y775 W M Q L G A F Y P F S R N H N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 Y625 S R D H A N Y Y S P R Q E L Y
Baker's Yeast Sacchar. cerevisiae P38138 954 110248 T677 R A H A H I D T K R R E P Y L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 95.4 83.9 N.A. 80 81.3 N.A. N.A. 50.4 N.A. 53.2 N.A. N.A. 37.7 N.A. 43
Protein Similarity: 100 98.9 97.6 89.5 N.A. 88.4 88.2 N.A. N.A. 66 N.A. 67.7 N.A. N.A. 53.1 N.A. 56.8
P-Site Identity: 100 86.6 86.6 80 N.A. 73.3 80 N.A. N.A. 6.6 N.A. 6.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 93.3 93.3 80 N.A. 80 80 N.A. N.A. 13.3 N.A. 13.3 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 32.7 23 N.A.
Protein Similarity: N.A. N.A. N.A. 50.5 43.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 9 9 0 0 9 0 9 9 0 0 0 % A
% Cys: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 9 0 25 0 9 0 0 0 0 0 0 0 0 % D
% Glu: 9 9 0 0 0 0 0 0 0 0 0 59 9 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 17 0 0 17 0 0 % F
% Gly: 9 0 0 0 25 0 0 9 0 0 9 0 0 0 0 % G
% His: 0 0 59 9 9 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 9 9 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 9 0 0 17 0 0 0 0 0 0 % K
% Leu: 0 0 17 9 0 50 34 0 42 9 0 9 0 9 9 % L
% Met: 0 9 0 0 0 0 0 9 0 0 0 0 0 9 0 % M
% Asn: 0 50 0 50 0 9 25 17 0 0 0 0 9 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 9 59 0 9 59 0 9 % P
% Gln: 0 0 9 0 0 9 0 0 9 0 50 9 0 0 0 % Q
% Arg: 59 9 9 0 0 9 0 0 0 17 17 9 0 0 42 % R
% Ser: 9 0 0 0 9 0 9 42 9 0 9 0 0 0 25 % S
% Thr: 0 0 0 0 17 0 0 9 0 0 0 0 9 0 0 % T
% Val: 0 9 0 9 0 0 0 0 9 0 0 0 0 0 0 % V
% Trp: 9 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 17 0 0 9 0 0 67 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _