KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAA
All Species:
30.3
Human Site:
Y298
Identified Species:
60.61
UniProt:
P10253
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10253
NP_000143.2
952
105319
Y298
L
Y
G
S
H
P
F
Y
L
A
L
E
D
G
G
Chimpanzee
Pan troglodytes
XP_001160562
952
105395
Y298
L
Y
G
S
H
P
F
Y
L
A
L
E
D
G
G
Rhesus Macaque
Macaca mulatta
XP_001109939
952
105411
Y298
L
Y
G
S
H
P
F
Y
L
A
L
E
D
G
G
Dog
Lupus familis
XP_850649
951
105652
Y298
L
Y
G
S
H
P
F
Y
L
A
L
E
D
G
G
Cat
Felis silvestris
Mouse
Mus musculus
P70699
953
106229
Y298
L
Y
G
S
H
P
F
Y
L
A
L
E
D
G
G
Rat
Rattus norvegicus
Q6P7A9
953
106188
Y298
L
Y
G
S
H
P
F
Y
L
A
L
E
D
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232641
930
104640
Y294
L
Y
G
A
H
P
F
Y
L
L
M
E
E
G
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921957
882
99143
A263
V
F
L
L
N
S
N
A
M
E
V
F
M
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392880
865
100033
D246
F
L
G
P
T
P
A
D
V
I
K
Q
Y
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787183
1049
116156
Y403
L
Y
G
V
H
P
F
Y
I
N
L
E
P
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7Y7
915
102380
Q277
S
P
L
N
V
V
D
Q
Y
T
Q
L
I
G
R
Baker's Yeast
Sacchar. cerevisiae
P38138
954
110248
F319
Y
G
S
I
P
F
M
F
S
S
S
S
T
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.4
83.9
N.A.
80
81.3
N.A.
N.A.
50.4
N.A.
53.2
N.A.
N.A.
37.7
N.A.
43
Protein Similarity:
100
98.9
97.6
89.5
N.A.
88.4
88.2
N.A.
N.A.
66
N.A.
67.7
N.A.
N.A.
53.1
N.A.
56.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
73.3
N.A.
0
N.A.
N.A.
13.3
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
33.3
N.A.
N.A.
26.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.5
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
9
9
0
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
9
0
0
0
0
50
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
67
9
0
9
% E
% Phe:
9
9
0
0
0
9
67
9
0
0
0
9
0
0
0
% F
% Gly:
0
9
75
0
0
0
0
0
0
0
0
0
0
67
67
% G
% His:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
9
9
0
0
9
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
67
9
17
9
0
0
0
0
59
9
59
9
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
9
0
9
0
9
0
0
% M
% Asn:
0
0
0
9
9
0
9
0
0
9
0
0
0
9
0
% N
% Pro:
0
9
0
9
9
75
0
0
0
0
0
0
9
0
9
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
9
9
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
9
0
9
50
0
9
0
0
9
9
9
9
0
17
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
9
0
0
9
0
0
% T
% Val:
9
0
0
9
9
9
0
0
9
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
67
0
0
0
0
0
67
9
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _