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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AR All Species: 5.15
Human Site: S494 Identified Species: 12.59
UniProt: P10275 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10275 NP_000035.2 919 98989 S494 Q G L A G Q E S D F T A P D V
Chimpanzee Pan troglodytes O97775 911 98384 G486 Q G L A G Q E G D F T A P D V
Rhesus Macaque Macaca mulatta Q6QT55 895 96519 G470 Q G L A G Q E G D F T A P D V
Dog Lupus familis XP_535225 780 85853 R403 G Y S S P G M R P D V S S P P
Cat Felis silvestris
Mouse Mus musculus P19091 899 98175 S474 Q G L T S Q E S D Y S A S E V
Rat Rattus norvegicus P15207 902 98199 G477 Q G L A S Q E G D F S A S E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510439 499 56093 Q122 T E A S Q S P Q Y G F E S L P
Chicken Gallus gallus P07812 786 85725 S409 D T E T S Q S S Q Y S F E S L
Frog Xenopus laevis P49844 776 84959 R399 G Y S S P G I R S D A S P S P
Zebra Danio Brachydanio rerio NP_001076592 868 95758 V447 Y G R S T A L V P R E R P P H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 95.8 32.5 N.A. 85.1 86.1 N.A. 30.3 35.6 33.5 39 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.8 96.4 46.5 N.A. 89.5 90.2 N.A. 40.7 51 46.9 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 0 N.A. 60 66.6 N.A. 0 13.3 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 93.3 13.3 N.A. 80 80 N.A. 6.6 33.3 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 40 0 10 0 0 0 0 10 50 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 50 20 0 0 0 30 0 % D
% Glu: 0 10 10 0 0 0 50 0 0 0 10 10 10 20 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 40 10 10 0 0 0 % F
% Gly: 20 60 0 0 30 20 0 30 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 50 0 0 0 10 0 0 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 20 0 10 0 20 0 0 0 50 20 30 % P
% Gln: 50 0 0 0 10 60 0 10 10 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 20 0 10 0 10 0 0 0 % R
% Ser: 0 0 20 40 30 10 10 30 10 0 30 20 40 20 0 % S
% Thr: 10 10 0 20 10 0 0 0 0 0 30 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 20 0 0 0 0 0 0 10 20 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _