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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1E
All Species:
29.09
Human Site:
T154
Identified Species:
64
UniProt:
P10412
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10412
NP_005312.1
219
21865
T154
P
K
K
S
A
K
K
T
P
K
K
A
K
K
P
Chimpanzee
Pan troglodytes
XP_001172808
221
22291
T155
P
K
K
S
I
K
K
T
P
K
K
V
K
K
P
Rhesus Macaque
Macaca mulatta
P40286
208
22075
T149
K
S
P
K
T
A
K
T
N
K
R
A
K
K
P
Dog
Lupus familis
XP_853847
290
29282
T209
P
K
K
S
A
K
K
T
P
K
K
A
K
K
P
Cat
Felis silvestris
Mouse
Mus musculus
P43274
219
21959
T154
A
K
K
S
T
K
K
T
P
K
K
A
K
K
P
Rat
Rattus norvegicus
P15865
219
21969
T154
P
K
K
S
T
K
K
T
P
K
K
A
K
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
T156
A
K
R
S
V
K
K
T
P
K
K
A
K
K
P
Chicken
Gallus gallus
P08284
219
22026
S153
K
A
A
A
V
K
K
S
P
K
K
A
K
K
P
Frog
Xenopus laevis
P06893
220
22422
S145
G
A
K
K
A
P
K
S
P
K
K
P
K
K
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
K182
K
K
T
A
E
N
K
K
T
E
K
A
K
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
V149
P
K
K
A
K
K
P
V
K
K
T
T
E
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.5
55.7
57.2
N.A.
94
95.4
N.A.
79.8
73.9
58.6
N.A.
N.A.
43.3
N.A.
N.A.
41.1
Protein Similarity:
100
87.3
68
62
N.A.
95.4
97.2
N.A.
87
79.4
66.3
N.A.
N.A.
52.3
N.A.
N.A.
50.6
P-Site Identity:
100
86.6
46.6
100
N.A.
86.6
93.3
N.A.
80
60
53.3
N.A.
N.A.
33.3
N.A.
N.A.
40
P-Site Similarity:
100
86.6
53.3
100
N.A.
86.6
93.3
N.A.
86.6
73.3
60
N.A.
N.A.
46.6
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
19
10
28
28
10
0
0
0
0
0
73
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
10
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
28
73
64
19
10
73
91
10
10
91
82
0
91
91
19
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% N
% Pro:
46
0
10
0
0
10
10
0
73
0
0
10
0
0
73
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
10
0
55
0
0
0
19
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
28
0
0
64
10
0
10
10
0
0
0
% T
% Val:
0
0
0
0
19
0
0
10
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _