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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1E
All Species:
16.67
Human Site:
T18
Identified Species:
36.67
UniProt:
P10412
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10412
NP_005312.1
219
21865
T18
A
P
A
P
A
E
K
T
P
V
K
K
K
A
R
Chimpanzee
Pan troglodytes
XP_001172808
221
22291
P19
P
A
P
A
E
K
T
P
V
K
K
K
A
K
K
Rhesus Macaque
Macaca mulatta
P40286
208
22075
T22
A
V
M
E
K
P
L
T
K
K
R
G
K
K
P
Dog
Lupus familis
XP_853847
290
29282
K73
P
R
P
N
P
T
Q
K
T
P
V
K
K
A
H
Cat
Felis silvestris
Mouse
Mus musculus
P43274
219
21959
T18
A
P
A
P
A
E
K
T
P
V
K
K
K
A
R
Rat
Rattus norvegicus
P15865
219
21969
T18
A
P
A
P
A
E
K
T
P
I
K
K
K
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
T18
P
S
A
P
A
E
K
T
P
T
K
K
R
A
K
Chicken
Gallus gallus
P08284
219
22026
A19
A
P
A
P
G
A
K
A
A
A
K
K
P
K
K
Frog
Xenopus laevis
P06893
220
22422
T22
E
P
A
A
A
K
K
T
K
K
Q
Q
P
K
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
K28
E
K
K
V
V
Q
K
K
A
S
G
S
A
G
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
H18
T
T
K
K
P
A
A
H
P
P
A
A
E
M
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.5
55.7
57.2
N.A.
94
95.4
N.A.
79.8
73.9
58.6
N.A.
N.A.
43.3
N.A.
N.A.
41.1
Protein Similarity:
100
87.3
68
62
N.A.
95.4
97.2
N.A.
87
79.4
66.3
N.A.
N.A.
52.3
N.A.
N.A.
50.6
P-Site Identity:
100
13.3
20
20
N.A.
100
93.3
N.A.
66.6
46.6
33.3
N.A.
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
26.6
26.6
N.A.
100
100
N.A.
80
53.3
60
N.A.
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
10
55
19
46
19
10
10
19
10
10
10
19
46
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
19
0
0
10
10
37
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
10
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
10
19
10
10
19
64
19
19
28
55
64
46
37
37
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
28
46
19
46
19
10
0
10
46
19
0
0
19
0
10
% P
% Gln:
0
0
0
0
0
10
10
0
0
0
10
10
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
10
0
10
0
28
% R
% Ser:
0
10
0
0
0
0
0
0
0
10
0
10
0
0
0
% S
% Thr:
10
10
0
0
0
10
10
55
10
10
0
0
0
0
10
% T
% Val:
0
10
0
10
10
0
0
0
10
19
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _