KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCL2
All Species:
18.18
Human Site:
Y108
Identified Species:
50
UniProt:
P10415
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10415
NP_000624.2
239
26266
Y108
G
D
D
F
S
R
R
Y
R
R
D
F
A
E
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095818
249
26641
Y110
G
D
D
F
S
R
R
Y
R
R
D
F
A
E
M
Dog
Lupus familis
XP_858876
323
35928
Q123
E
P
L
V
G
Q
V
Q
E
W
M
V
A
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
P10417
236
26407
Y105
G
D
D
F
S
R
R
Y
R
R
D
F
A
E
M
Rat
Rattus norvegicus
P49950
236
26604
Y105
G
D
D
F
S
R
R
Y
R
R
D
F
A
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512467
195
20886
Q79
V
T
P
G
S
A
Q
Q
R
F
T
Q
V
S
D
Chicken
Gallus gallus
Q00709
233
25669
Y102
G
D
E
F
S
R
R
Y
Q
R
D
F
A
Q
M
Frog
Xenopus laevis
Q91827
228
25050
I103
F
S
E
I
S
T
Q
I
H
V
T
P
G
T
A
Zebra Danio
Brachydanio rerio
XP_001341214
209
23415
S92
S
K
Q
L
H
V
T
S
I
T
A
H
Q
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
79.9
20.7
N.A.
89.9
89.1
N.A.
39.3
74
37.2
44.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
82.3
31.5
N.A.
91.2
90.3
N.A.
55.2
78.6
54.3
60.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
6.6
N.A.
100
100
N.A.
13.3
80
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
20
N.A.
100
100
N.A.
20
100
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
0
12
0
67
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
56
45
0
0
0
0
0
0
0
56
0
0
0
12
% D
% Glu:
12
0
23
0
0
0
0
0
12
0
0
0
0
45
0
% E
% Phe:
12
0
0
56
0
0
0
0
0
12
0
56
0
0
12
% F
% Gly:
56
0
0
12
12
0
0
0
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
12
0
0
0
12
0
0
12
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
12
12
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
12
0
0
0
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
56
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
12
0
0
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
12
0
0
12
23
23
12
0
0
12
12
12
0
% Q
% Arg:
0
0
0
0
0
56
56
0
56
56
0
0
0
12
0
% R
% Ser:
12
12
0
0
78
0
0
12
0
0
0
0
0
12
0
% S
% Thr:
0
12
0
0
0
12
12
0
0
12
23
0
0
12
0
% T
% Val:
12
0
0
12
0
12
12
0
0
12
0
12
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
56
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _