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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPP1
All Species:
8.48
Human Site:
Y33
Identified Species:
26.67
UniProt:
P10451
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10451
NP_000573.1
314
35423
Y33
S
S
E
E
K
Q
L
Y
N
K
Y
P
D
A
V
Chimpanzee
Pan troglodytes
XP_517332
314
35276
Y33
S
S
E
E
K
Q
L
Y
N
K
Y
P
D
A
V
Rhesus Macaque
Macaca mulatta
XP_001093307
292
32933
Y15
F
C
L
L
G
I
A
Y
A
L
P
V
K
Q
A
Dog
Lupus familis
XP_535649
326
36145
K39
E
P
E
E
S
C
G
K
L
T
M
R
I
A
V
Cat
Felis silvestris
Mouse
Mus musculus
P10923
294
32441
S16
C
L
F
G
I
A
S
S
L
P
V
K
V
T
D
Rat
Rattus norvegicus
P08721
317
34944
Y33
S
S
E
E
K
A
H
Y
S
K
H
S
D
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515967
305
33985
N27
K
R
S
G
P
E
A
N
S
G
S
S
E
E
K
Chicken
Gallus gallus
P23498
264
29144
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
86.3
43.5
N.A.
64.6
63.7
N.A.
41.4
27.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
88.8
58.2
N.A.
76.4
78.2
N.A.
54.7
44.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
26.6
N.A.
0
66.6
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
26.6
N.A.
0
80
N.A.
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
25
25
0
13
0
0
0
0
50
13
% A
% Cys:
13
13
0
0
0
13
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
13
% D
% Glu:
13
0
50
50
0
13
0
0
0
0
0
0
13
13
0
% E
% Phe:
13
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
25
13
0
13
0
0
13
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
13
0
0
0
13
0
0
0
0
% H
% Ile:
0
0
0
0
13
13
0
0
0
0
0
0
13
0
0
% I
% Lys:
13
0
0
0
38
0
0
13
0
38
0
13
13
0
13
% K
% Leu:
0
13
13
13
0
0
25
0
25
13
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
25
0
0
0
0
0
0
% N
% Pro:
0
13
0
0
13
0
0
0
0
13
13
25
0
0
0
% P
% Gln:
0
0
0
0
0
25
0
0
0
0
0
0
0
13
0
% Q
% Arg:
0
13
0
0
0
0
0
0
0
0
0
13
0
0
0
% R
% Ser:
38
38
13
0
13
0
13
13
25
0
13
25
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
13
0
0
0
13
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
13
13
13
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
25
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _