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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLAT All Species: 12.12
Human Site: T322 Identified Species: 16.67
UniProt: P10515 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10515 NP_001922.2 647 68997 T322 K P Q V P P P T P P P V A A V
Chimpanzee Pan troglodytes XP_522180 647 68973 T322 K P Q A P P P T P P P V A A V
Rhesus Macaque Macaca mulatta XP_001107013 647 68918 T322 K P Q A P P P T P P P V A T V
Dog Lupus familis XP_546524 647 68802 T322 K P Q A P P S T P P P V A P V
Cat Felis silvestris
Mouse Mus musculus Q8BMF4 642 67923 A321 K P Q A A P P A P P P V A A V
Rat Rattus norvegicus P08461 632 67147 V312 K P Q A P P P V P P P V A A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509202 536 56600 A228 S P Q P A S P A P P A A R P A
Chicken Gallus gallus XP_417933 681 72018 P351 K A Q V P P P P P S P P V V A
Frog Xenopus laevis NP_001082239 628 66845 P299 I K P Q H A P P T P T A A S V
Zebra Danio Brachydanio rerio NP_997832 652 69250 V322 P P P A P T L V A T P P P A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609118 512 54233 A206 P P A A A P A A A A P P P A P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19749 507 53448 Y201 P S P P A Q M Y Q A P S V P K
Sea Urchin Strong. purpuratus XP_001190217 487 52117 P181 P P P A A A T P S T P P P P P
Poplar Tree Populus trichocarpa XP_002303212 512 55370 P206 K P A S L P E P K I S K P S A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q5M729 539 58449 P233 Q P S S P P E P K A S K P S T
Baker's Yeast Sacchar. cerevisiae P12695 482 51800 A176 A P Q G R I F A S P L A K T I
Red Bread Mold Neurospora crassa P20285 458 48601 A152 T A S A P T P A P T P A P E P
Conservation
Percent
Protein Identity: 100 99.2 98.1 89.4 N.A. 85.6 85.1 N.A. 70.3 72 72.8 71.9 N.A. 42 N.A. 41.7 39.8
Protein Similarity: 100 99.2 98.6 92.8 N.A. 90.2 89.6 N.A. 74.5 78.4 82.6 78.9 N.A. 53.9 N.A. 55 54.1
P-Site Identity: 100 93.3 86.6 80 N.A. 80 86.6 N.A. 33.3 53.3 26.6 26.6 N.A. 26.6 N.A. 6.6 13.3
P-Site Similarity: 100 93.3 86.6 80 N.A. 80 86.6 N.A. 33.3 53.3 33.3 26.6 N.A. 26.6 N.A. 6.6 13.3
Percent
Protein Identity: 36.3 N.A. N.A. 38.6 33.5 36.6
Protein Similarity: 50.2 N.A. N.A. 53 48.2 48.8
P-Site Identity: 20 N.A. N.A. 20 20 26.6
P-Site Similarity: 26.6 N.A. N.A. 33.3 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 12 12 53 30 12 6 30 12 18 6 24 42 36 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 12 0 0 0 0 0 0 6 0 % E
% Phe: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 6 0 0 0 0 6 0 0 0 6 0 0 0 0 6 % I
% Lys: 48 6 0 0 0 0 0 0 12 0 0 12 6 0 6 % K
% Leu: 0 0 0 0 6 0 6 0 0 0 6 0 0 0 0 % L
% Met: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 24 77 24 12 53 59 53 30 53 53 71 24 36 24 18 % P
% Gln: 6 0 53 6 0 6 0 0 6 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 6 0 0 0 0 0 0 0 6 0 0 % R
% Ser: 6 6 12 12 0 6 6 0 12 6 12 6 0 18 0 % S
% Thr: 6 0 0 0 0 12 6 24 6 18 6 0 0 12 6 % T
% Val: 0 0 0 12 0 0 0 12 0 0 0 36 12 6 42 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _