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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLAT
All Species:
9.7
Human Site:
T385
Identified Species:
13.33
UniProt:
P10515
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10515
NP_001922.2
647
68997
T385
T
G
P
D
G
R
I
T
K
K
D
I
D
S
F
Chimpanzee
Pan troglodytes
XP_522180
647
68973
T385
T
G
P
D
G
R
I
T
K
K
D
I
D
S
F
Rhesus Macaque
Macaca mulatta
XP_001107013
647
68918
T385
T
G
P
D
G
R
I
T
K
K
D
I
D
S
F
Dog
Lupus familis
XP_546524
647
68802
I385
T
G
P
E
G
R
I
I
K
K
D
V
D
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF4
642
67923
I384
G
R
I
I
K
K
D
I
D
S
F
V
P
S
K
Rat
Rattus norvegicus
P08461
632
67147
I375
G
R
I
I
K
K
D
I
D
S
F
V
P
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509202
536
56600
A291
S
R
A
A
P
A
P
A
A
A
V
P
S
L
T
Chicken
Gallus gallus
XP_417933
681
72018
P414
A
Q
V
K
G
T
G
P
D
G
R
I
T
K
K
Frog
Xenopus laevis
NP_001082239
628
66845
K362
G
P
E
G
R
I
T
K
K
D
I
D
S
F
V
Zebra Danio
Brachydanio rerio
NP_997832
652
69250
K385
P
D
G
R
V
T
K
K
D
I
D
S
F
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609118
512
54233
A269
K
A
A
A
K
P
A
A
A
A
P
A
K
A
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
S264
A
P
A
K
G
A
T
S
T
T
T
Q
A
V
S
Sea Urchin
Strong. purpuratus
XP_001190217
487
52117
G244
D
I
E
S
Y
V
P
G
V
A
G
V
P
M
P
Poplar Tree
Populus trichocarpa
XP_002303212
512
55370
K269
G
K
E
A
P
A
T
K
P
V
A
K
D
T
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5M729
539
58449
P296
G
K
G
A
T
A
K
P
S
K
S
T
D
S
K
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
A239
A
A
T
S
S
T
T
A
G
S
A
P
S
P
S
Red Bread Mold
Neurospora crassa
P20285
458
48601
A215
E
D
V
K
K
A
L
A
S
A
P
A
A
G
A
Conservation
Percent
Protein Identity:
100
99.2
98.1
89.4
N.A.
85.6
85.1
N.A.
70.3
72
72.8
71.9
N.A.
42
N.A.
41.7
39.8
Protein Similarity:
100
99.2
98.6
92.8
N.A.
90.2
89.6
N.A.
74.5
78.4
82.6
78.9
N.A.
53.9
N.A.
55
54.1
P-Site Identity:
100
100
100
80
N.A.
6.6
0
N.A.
0
13.3
6.6
6.6
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
20
20
N.A.
6.6
13.3
6.6
6.6
N.A.
6.6
N.A.
13.3
6.6
Percent
Protein Identity:
36.3
N.A.
N.A.
38.6
33.5
36.6
Protein Similarity:
50.2
N.A.
N.A.
53
48.2
48.8
P-Site Identity:
6.6
N.A.
N.A.
20
0
0
P-Site Similarity:
13.3
N.A.
N.A.
20
0
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
12
18
24
0
30
6
24
12
24
12
12
12
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
12
0
18
0
0
12
0
24
6
30
6
36
0
0
% D
% Glu:
6
0
18
6
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
12
0
6
6
24
% F
% Gly:
30
24
12
6
36
0
6
6
6
6
6
0
0
6
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
6
12
12
0
6
24
18
0
6
6
24
0
0
0
% I
% Lys:
6
12
0
18
24
12
12
18
30
30
0
6
6
6
24
% K
% Leu:
0
0
0
0
0
0
6
0
0
0
0
0
0
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
6
12
24
0
12
6
12
12
6
0
12
12
18
6
18
% P
% Gln:
0
6
0
0
0
0
0
0
0
0
0
6
0
0
0
% Q
% Arg:
0
18
0
6
6
24
0
0
0
0
6
0
0
0
0
% R
% Ser:
6
0
0
12
6
0
0
6
12
18
6
6
18
36
18
% S
% Thr:
24
0
6
0
6
18
24
18
6
6
6
6
6
12
6
% T
% Val:
0
0
12
0
6
6
0
0
6
6
6
24
0
12
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _