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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXN
All Species:
30
Human Site:
S44
Identified Species:
50.77
UniProt:
P10599
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10599
NP_003320.2
105
11737
S44
M
I
K
P
F
F
H
S
L
S
E
K
Y
S
N
Chimpanzee
Pan troglodytes
XP_001142154
323
34866
S262
M
I
K
P
F
F
H
S
L
S
E
K
Y
S
N
Rhesus Macaque
Macaca mulatta
P29451
105
11719
S44
M
I
K
P
F
F
H
S
L
S
E
K
Y
S
N
Dog
Lupus familis
XP_532029
219
24533
S158
M
I
K
P
F
F
H
S
L
S
E
K
Y
S
N
Cat
Felis silvestris
Mouse
Mus musculus
P10639
105
11657
S44
M
I
K
P
F
F
H
S
L
C
D
K
Y
S
N
Rat
Rattus norvegicus
P11232
105
11655
S44
M
I
K
P
F
F
H
S
L
C
D
K
Y
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509068
105
11826
S44
M
I
K
P
F
F
H
S
L
S
E
K
D
P
D
Chicken
Gallus gallus
P08629
105
11682
S44
M
I
K
P
F
F
H
S
L
C
D
K
F
G
D
Frog
Xenopus laevis
NP_001091381
105
11846
K44
M
I
A
P
V
F
E
K
L
S
V
E
N
P
D
Zebra Danio
Brachydanio rerio
NP_001002461
107
11856
L44
T
I
G
P
Y
F
K
L
L
S
E
K
P
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V429
114
12677
E52
M
I
S
P
K
L
V
E
L
S
T
Q
F
A
D
Honey Bee
Apis mellifera
XP_392963
105
11998
E44
M
I
G
P
K
V
E
E
L
S
M
E
M
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C9Y6
140
15316
E69
I
V
A
P
F
F
I
E
L
S
E
K
H
S
S
Baker's Yeast
Sacchar. cerevisiae
P22803
104
11185
K43
M
I
A
P
M
I
E
K
F
A
E
Q
Y
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.5
97.1
44.2
N.A.
87.6
88.5
N.A.
80.9
70.4
60
62.6
N.A.
47.3
49.5
N.A.
N.A.
Protein Similarity:
100
32.5
98
47.9
N.A.
93.3
93.3
N.A.
88.5
83.8
72.3
73.8
N.A.
63.1
69.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
80
66.6
40
53.3
N.A.
33.3
33.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
86.6
53.3
60
N.A.
60
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.5
48.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55
64.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
0
0
0
0
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
22
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
22
0
8
0
43
% D
% Glu:
0
0
0
0
0
0
22
22
0
0
58
15
0
15
0
% E
% Phe:
0
0
0
0
65
79
0
0
8
0
0
0
15
0
0
% F
% Gly:
0
0
15
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
58
0
0
0
0
0
8
0
0
% H
% Ile:
8
93
0
0
0
8
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
58
0
15
0
8
15
0
0
0
72
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
8
93
0
0
0
0
0
0
% L
% Met:
86
0
0
0
8
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
50
% N
% Pro:
0
0
0
100
0
0
0
0
0
0
0
0
8
15
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
58
0
72
0
0
0
58
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
8
0
0
8
8
8
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _