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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXN
All Species:
30.61
Human Site:
S46
Identified Species:
51.79
UniProt:
P10599
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10599
NP_003320.2
105
11737
S46
K
P
F
F
H
S
L
S
E
K
Y
S
N
V
I
Chimpanzee
Pan troglodytes
XP_001142154
323
34866
S264
K
P
F
F
H
S
L
S
E
K
Y
S
N
V
I
Rhesus Macaque
Macaca mulatta
P29451
105
11719
S46
K
P
F
F
H
S
L
S
E
K
Y
S
N
V
V
Dog
Lupus familis
XP_532029
219
24533
S160
K
P
F
F
H
S
L
S
E
K
Y
S
N
V
V
Cat
Felis silvestris
Mouse
Mus musculus
P10639
105
11657
C46
K
P
F
F
H
S
L
C
D
K
Y
S
N
V
V
Rat
Rattus norvegicus
P11232
105
11655
C46
K
P
F
F
H
S
L
C
D
K
Y
S
N
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509068
105
11826
S46
K
P
F
F
H
S
L
S
E
K
D
P
D
V
V
Chicken
Gallus gallus
P08629
105
11682
C46
K
P
F
F
H
S
L
C
D
K
F
G
D
V
V
Frog
Xenopus laevis
NP_001091381
105
11846
S46
A
P
V
F
E
K
L
S
V
E
N
P
D
V
V
Zebra Danio
Brachydanio rerio
NP_001002461
107
11856
S46
G
P
Y
F
K
L
L
S
E
K
P
E
N
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V429
114
12677
S54
S
P
K
L
V
E
L
S
T
Q
F
A
D
N
V
Honey Bee
Apis mellifera
XP_392963
105
11998
S46
G
P
K
V
E
E
L
S
M
E
M
E
D
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C9Y6
140
15316
S71
A
P
F
F
I
E
L
S
E
K
H
S
S
L
M
Baker's Yeast
Sacchar. cerevisiae
P22803
104
11185
A45
A
P
M
I
E
K
F
A
E
Q
Y
S
D
A
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.5
97.1
44.2
N.A.
87.6
88.5
N.A.
80.9
70.4
60
62.6
N.A.
47.3
49.5
N.A.
N.A.
Protein Similarity:
100
32.5
98
47.9
N.A.
93.3
93.3
N.A.
88.5
83.8
72.3
73.8
N.A.
63.1
69.5
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
80
80
N.A.
73.3
60
33.3
46.6
N.A.
20
33.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
86.6
53.3
53.3
N.A.
53.3
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.5
48.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55
64.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
0
0
0
0
8
0
0
0
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
22
0
8
0
43
0
0
% D
% Glu:
0
0
0
0
22
22
0
0
58
15
0
15
0
0
0
% E
% Phe:
0
0
65
79
0
0
8
0
0
0
15
0
0
0
0
% F
% Gly:
15
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
58
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
22
% I
% Lys:
58
0
15
0
8
15
0
0
0
72
0
0
0
8
0
% K
% Leu:
0
0
0
8
0
8
93
0
0
0
0
0
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
50
8
8
% N
% Pro:
0
100
0
0
0
0
0
0
0
0
8
15
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
58
0
72
0
0
0
58
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
8
8
8
0
0
0
8
0
0
0
0
72
58
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
50
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _