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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX5B
All Species:
28.18
Human Site:
Y62
Identified Species:
51.67
UniProt:
P10606
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10606
NP_001853.2
129
13696
Y62
A
K
K
G
L
D
P
Y
N
V
L
A
P
K
G
Chimpanzee
Pan troglodytes
XP_001154903
129
13731
Y62
A
K
K
G
L
D
P
Y
N
I
L
A
P
K
G
Rhesus Macaque
Macaca mulatta
XP_001100566
129
13770
Y62
A
R
K
G
L
D
P
Y
N
I
L
P
P
K
G
Dog
Lupus familis
XP_534921
129
13832
Y62
E
R
K
G
L
D
P
Y
N
I
L
A
P
K
A
Cat
Felis silvestris
Mouse
Mus musculus
P19536
128
13794
Y61
A
Q
K
G
L
D
P
Y
N
M
L
P
P
K
A
Rat
Rattus norvegicus
P12075
129
13896
Y62
A
Q
R
G
L
D
P
Y
N
M
L
P
P
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520188
119
13429
A60
N
L
L
A
P
K
G
A
A
G
T
R
E
E
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085056
131
14830
Y64
M
K
K
G
L
D
P
Y
S
I
L
K
P
K
S
Zebra Danio
Brachydanio rerio
XP_001342184
127
13923
Y60
S
K
K
G
L
D
P
Y
N
I
L
K
P
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609046
120
13560
F60
N
P
F
D
M
K
V
F
K
R
G
A
G
T
K
Honey Bee
Apis mellifera
XP_624987
122
13921
I61
D
P
Y
H
M
K
A
I
E
I
S
R
D
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786378
128
14191
L60
G
D
S
D
P
F
Q
L
N
V
R
R
V
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P06809
186
20595
D89
M
E
G
V
D
V
F
D
M
K
P
L
D
A
S
Conservation
Percent
Protein Identity:
100
96.9
87.5
79.8
N.A.
82.9
81.4
N.A.
63.5
N.A.
57.2
65.1
N.A.
41.8
38.7
N.A.
44.9
Protein Similarity:
100
99.2
96.9
90.6
N.A.
89.1
89.9
N.A.
75.9
N.A.
72.5
80.6
N.A.
57.3
50.3
N.A.
59.6
P-Site Identity:
100
93.3
80
73.3
N.A.
73.3
66.6
N.A.
0
N.A.
66.6
73.3
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
6.6
N.A.
80
86.6
N.A.
20
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
0
8
0
0
8
8
8
0
0
31
0
16
31
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
16
8
62
0
8
0
0
0
0
16
0
0
% D
% Glu:
8
8
0
0
0
0
0
0
8
0
0
0
8
8
8
% E
% Phe:
0
0
8
0
0
8
8
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
62
0
0
8
0
0
8
8
0
8
0
24
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
47
0
0
0
0
0
% I
% Lys:
0
31
54
0
0
24
0
0
8
8
0
16
0
62
8
% K
% Leu:
0
8
8
0
62
0
0
8
0
0
62
8
0
0
0
% L
% Met:
16
0
0
0
16
0
0
0
8
16
0
0
0
0
0
% M
% Asn:
16
0
0
0
0
0
0
0
62
0
0
0
0
0
0
% N
% Pro:
0
16
0
0
16
0
62
0
0
0
8
24
62
0
8
% P
% Gln:
0
16
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
16
8
0
0
0
0
0
0
8
8
24
0
0
0
% R
% Ser:
8
0
8
0
0
0
0
0
8
0
8
0
0
8
16
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% T
% Val:
0
0
0
8
0
8
8
0
0
16
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _