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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSA
All Species:
10.91
Human Site:
S287
Identified Species:
21.82
UniProt:
P10619
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10619
NP_000299.2
480
54466
S287
P
C
A
G
G
V
P
S
H
F
R
Y
E
K
D
Chimpanzee
Pan troglodytes
XP_001159669
495
55859
S302
P
C
A
G
G
V
P
S
H
F
R
Y
E
K
D
Rhesus Macaque
Macaca mulatta
XP_001106032
494
55727
S301
P
C
A
G
G
V
P
S
H
F
R
Y
E
K
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P16675
474
53826
G282
P
C
A
G
G
V
P
G
R
H
R
Y
E
D
T
Rat
Rattus norvegicus
NP_001011959
456
51197
C276
I
Y
N
L
Y
A
P
C
A
G
G
V
P
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026662
471
53136
G276
P
C
A
G
G
V
P
G
S
M
R
Y
E
G
D
Frog
Xenopus laevis
NP_001088109
470
52915
G277
S
C
P
G
G
A
P
G
E
V
K
D
N
G
D
Zebra Danio
Brachydanio rerio
NP_956844
471
53005
Q276
P
C
P
G
G
V
G
Q
R
F
G
F
E
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52717
469
53628
P271
D
L
Y
R
D
C
D
P
N
P
S
V
N
S
K
Sea Urchin
Strong. purpuratus
XP_798670
470
52291
S284
L
D
C
Y
N
G
P
S
S
V
K
S
P
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7B2
497
55814
R301
S
L
S
A
F
D
I
R
S
L
P
S
S
L
L
Baker's Yeast
Sacchar. cerevisiae
P38109
508
57620
T311
S
L
P
C
I
V
A
T
A
Y
C
D
S
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
94.5
N.A.
N.A.
86.8
78.3
N.A.
N.A.
65.8
61.6
63.1
N.A.
N.A.
N.A.
39.3
47.2
Protein Similarity:
100
95.1
94.9
N.A.
N.A.
92
84.7
N.A.
N.A.
77.7
75.8
77
N.A.
N.A.
N.A.
58.9
65.4
P-Site Identity:
100
100
100
N.A.
N.A.
66.6
6.6
N.A.
N.A.
73.3
33.3
46.6
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
66.6
6.6
N.A.
N.A.
73.3
40
53.3
N.A.
N.A.
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
28.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.7
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
42
9
0
17
9
0
17
0
0
0
0
9
0
% A
% Cys:
0
59
9
9
0
9
0
9
0
0
9
0
0
0
0
% C
% Asp:
9
9
0
0
9
9
9
0
0
0
0
17
0
9
42
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
0
50
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
34
0
9
0
0
0
% F
% Gly:
0
0
0
59
59
9
9
25
0
9
17
0
0
25
9
% G
% His:
0
0
0
0
0
0
0
0
25
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
17
0
0
25
9
% K
% Leu:
9
25
0
9
0
0
0
0
0
9
0
0
0
17
25
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
0
9
0
0
0
17
9
0
% N
% Pro:
50
0
25
0
0
0
67
9
0
9
9
0
17
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
9
17
0
42
0
0
0
9
% R
% Ser:
25
0
9
0
0
0
0
34
25
0
9
17
17
9
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
0
59
0
0
0
17
0
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
9
9
0
0
0
0
9
0
42
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _