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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSA
All Species:
13.03
Human Site:
T295
Identified Species:
26.06
UniProt:
P10619
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10619
NP_000299.2
480
54466
T295
H
F
R
Y
E
K
D
T
V
V
V
Q
D
L
G
Chimpanzee
Pan troglodytes
XP_001159669
495
55859
T310
H
F
R
Y
E
K
D
T
V
V
V
Q
D
L
G
Rhesus Macaque
Macaca mulatta
XP_001106032
494
55727
T309
H
F
R
Y
E
K
D
T
V
V
V
Q
D
L
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P16675
474
53826
L290
R
H
R
Y
E
D
T
L
V
V
Q
D
F
G
N
Rat
Rattus norvegicus
NP_001011959
456
51197
D284
A
G
G
V
P
G
R
D
R
S
E
D
T
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026662
471
53136
Y284
S
M
R
Y
E
G
D
Y
L
I
T
H
D
L
G
Frog
Xenopus laevis
NP_001088109
470
52915
H285
E
V
K
D
N
G
D
H
I
I
V
Y
H
P
G
Zebra Danio
Brachydanio rerio
NP_956844
471
53005
Q284
R
F
G
F
E
N
G
Q
F
V
I
R
D
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52717
469
53628
R279
N
P
S
V
N
S
K
R
M
K
H
M
L
R
G
Sea Urchin
Strong. purpuratus
XP_798670
470
52291
T292
S
V
K
S
P
L
L
T
R
Y
Q
F
D
M
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7B2
497
55814
Q309
S
L
P
S
S
L
L
Q
L
G
K
T
E
K
R
Baker's Yeast
Sacchar. cerevisiae
P38109
508
57620
L319
A
Y
C
D
S
A
L
L
E
P
Y
I
N
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
94.5
N.A.
N.A.
86.8
78.3
N.A.
N.A.
65.8
61.6
63.1
N.A.
N.A.
N.A.
39.3
47.2
Protein Similarity:
100
95.1
94.9
N.A.
N.A.
92
84.7
N.A.
N.A.
77.7
75.8
77
N.A.
N.A.
N.A.
58.9
65.4
P-Site Identity:
100
100
100
N.A.
N.A.
33.3
6.6
N.A.
N.A.
46.6
20
40
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
33.3
6.6
N.A.
N.A.
60
40
60
N.A.
N.A.
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
28.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.7
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
9
42
9
0
0
0
17
50
0
0
% D
% Glu:
9
0
0
0
50
0
0
0
9
0
9
0
9
0
0
% E
% Phe:
0
34
0
9
0
0
0
0
9
0
0
9
9
0
0
% F
% Gly:
0
9
17
0
0
25
9
0
0
9
0
0
0
9
67
% G
% His:
25
9
0
0
0
0
0
9
0
0
9
9
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
17
9
9
0
0
0
% I
% Lys:
0
0
17
0
0
25
9
0
0
9
9
0
0
9
0
% K
% Leu:
0
9
0
0
0
17
25
17
17
0
0
0
9
50
0
% L
% Met:
0
9
0
0
0
0
0
0
9
0
0
9
0
9
0
% M
% Asn:
9
0
0
0
17
9
0
0
0
0
0
0
9
0
9
% N
% Pro:
0
9
9
0
17
0
0
0
0
9
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
17
0
0
17
25
0
0
9
% Q
% Arg:
17
0
42
0
0
0
9
9
17
0
0
9
0
9
9
% R
% Ser:
25
0
9
17
17
9
0
0
0
9
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
34
0
0
9
9
9
9
0
% T
% Val:
0
17
0
17
0
0
0
0
34
42
34
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
42
0
0
0
9
0
9
9
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _