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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSA
All Species:
28.48
Human Site:
Y50
Identified Species:
56.97
UniProt:
P10619
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10619
NP_000299.2
480
54466
Y50
K
Q
P
S
F
R
Q
Y
S
G
Y
L
K
G
S
Chimpanzee
Pan troglodytes
XP_001159669
495
55859
Y65
K
Q
P
S
F
R
Q
Y
S
G
Y
L
K
G
S
Rhesus Macaque
Macaca mulatta
XP_001106032
494
55727
Y64
K
Q
P
S
F
R
Q
Y
S
G
Y
L
K
G
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P16675
474
53826
Y45
K
Q
P
S
F
R
Q
Y
S
G
Y
L
R
A
S
Rat
Rattus norvegicus
NP_001011959
456
51197
Q39
C
L
P
G
L
A
K
Q
P
S
F
R
Q
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026662
471
53136
F39
K
Q
P
S
F
R
H
F
S
G
H
L
C
I
G
Frog
Xenopus laevis
NP_001088109
470
52915
Y40
K
Q
P
S
F
R
Q
Y
S
G
F
L
N
V
S
Zebra Danio
Brachydanio rerio
NP_956844
471
53005
Y39
K
Q
P
S
F
R
H
Y
S
G
Y
F
N
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52717
469
53628
Y34
F
E
P
N
F
K
H
Y
S
G
F
F
Q
V
S
Sea Urchin
Strong. purpuratus
XP_798670
470
52291
Y47
T
Q
P
T
F
R
H
Y
S
G
Y
L
N
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7B2
497
55814
L64
D
K
E
H
G
K
N
L
W
Y
Y
F
I
E
S
Baker's Yeast
Sacchar. cerevisiae
P38109
508
57620
Y74
I
S
S
V
D
T
D
Y
S
L
R
L
R
T
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
94.5
N.A.
N.A.
86.8
78.3
N.A.
N.A.
65.8
61.6
63.1
N.A.
N.A.
N.A.
39.3
47.2
Protein Similarity:
100
95.1
94.9
N.A.
N.A.
92
84.7
N.A.
N.A.
77.7
75.8
77
N.A.
N.A.
N.A.
58.9
65.4
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
13.3
N.A.
N.A.
60
80
66.6
N.A.
N.A.
N.A.
40
66.6
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
33.3
N.A.
N.A.
73.3
86.6
73.3
N.A.
N.A.
N.A.
73.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
28.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.7
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
0
17
9
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
9
0
0
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
9
0
0
0
75
0
0
9
0
0
25
25
0
0
0
% F
% Gly:
0
0
0
9
9
0
0
0
0
75
0
0
0
25
9
% G
% His:
0
0
0
9
0
0
34
0
0
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% I
% Lys:
59
9
0
0
0
17
9
0
0
0
0
0
25
0
0
% K
% Leu:
0
9
0
0
9
0
0
9
0
9
0
67
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
0
0
0
0
0
25
0
0
% N
% Pro:
0
0
84
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
67
0
0
0
0
42
9
0
0
0
0
17
0
0
% Q
% Arg:
0
0
0
0
0
67
0
0
0
0
9
9
17
0
0
% R
% Ser:
0
9
9
59
0
0
0
0
84
9
0
0
0
0
75
% S
% Thr:
9
0
0
9
0
9
0
0
0
0
0
0
0
9
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
0
0
25
9
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
9
59
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _